383426-39-9

Upstream product

• 33252-30-1 2-chloro-4-pyridinenitrile 
• 2627-86-3 (S)-1-phenyl-ethylamine 
• 383426-37-7 (2-fluoropyridin-4-yl)methan-N-hydroxyimine 
• 3939-14-8 2-fluoropyridine-4-carbonitrile 
• 461-87-0 2-fluoro-4-methylpyridine 
• 7440-44-0 pyrographite 
• 14906-59-3 4-cyanopyridine N-oxide 

Downstream Products

• 383426-38-8 2-{[(1S)-1-phenylethyl]amino}isonicotinaldehyde 

Relevant academic research and scientific papers

Synthesis of substituted imidazoles

The present invention prepares imidazoles by the selective closure of a keto-amide to form the imidazolyl ring. In particular, the present invention selectively closes a keto-amide substituted with three rings to form a tri-substituted imidazole.

Practical routes toward the synthesis of 2-halo- and 2-alkylamino-4-pyridinecarboxaldehydes

We recently required an efficient synthesis of 2-halo- and 2-alkylamino-4-pyridinecarboxaldehydes. Several routes to these compounds were investigated resulting in efficient and practical procedures from readily available and inexpensive starting materials.