38345-23-2 Usage
Uses
Used in Pharmaceutical Industry:
3-PHENYL-4H-1,2,4-TRIAZOL-4-AMINE is used as a key intermediate in the synthesis of various pharmaceuticals for its potential anti-cancer, anti-inflammatory, and anti-microbial properties. Its unique structure allows for the development of drugs that can target specific biological pathways, offering new treatment options for a range of diseases.
Used in Agrochemical Industry:
In the agrochemical sector, 3-PHENYL-4H-1,2,4-TRIAZOL-4-AMINE serves as a vital component in the creation of pesticides and other crop protection agents. Its incorporation into these products leverages its anti-microbial properties to protect crops from diseases and pests, thereby enhancing agricultural productivity and crop quality.
Used in Organic Synthesis:
3-PHENYL-4H-1,2,4-TRIAZOL-4-AMINE is utilized as a versatile building block in organic synthesis, enabling the production of a wide array of organic compounds. Its reactivity and structural features make it suitable for the creation of complex molecules with specific functions, contributing to the advancement of material science and chemical research.
Check Digit Verification of cas no
The CAS Registry Mumber 38345-23-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,8,3,4 and 5 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 38345-23:
(7*3)+(6*8)+(5*3)+(4*4)+(3*5)+(2*2)+(1*3)=122
122 % 10 = 2
So 38345-23-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H8N4/c9-12-6-10-11-8(12)7-4-2-1-3-5-7/h1-6H,9H2
38345-23-2Relevant academic research and scientific papers
Thermal rearrangement of allyl substituted unsymmetric 4H-1,2,4-triazoles to the corresponding 1H-1,2,4-triazoles
Jorgensen, Kare B.,Olsen, Ragnhild B.,Carlsen, Per H.J.
, p. 481 - 495 (2007/10/03)
A series of neat 4-(2-alkenyl) substituted 5-methyl-3-phenyl-4H-1,2,4- triazoles were thermolyzed at 320°C producing a rearrangement products, of which the regioisomeric 1- and 2-substituted triazoles were the main products. The group migrations were rationalized in terms of consecutive S N2-type reactions. This mechanism was supported by a study of the alkylations of the triazoles which gave similar product mixtures. 4-(2-alkenyl) substituted 3-phenyl-4H-1,2,4-triazoles, on the other hand, gave predominantly elimination products.
A Study on Ester Formylhydrazones
Ikizler, Aykut A.,Yildirim, Nuri
, p. 377 - 380 (2007/10/03)
A series of ester formylhydrazones 2 were synthesized from the reaction of alkyl imidate hydrochlorides 1 with formylhydrazine. Treatment of 2 with hydrazine hydrate, ethyl carbazate and tert-butyl carbazate led to the formation of 3-alkyl-4-amino-, 3-alkyl-4-ethoxycarbonylamino- and 3-alkyl-4-tert-butoxycarbonylamino-4H-1,2,4-triazoles 3-5, respectively. Reaction of compounds 2 with formylhydrazine gave N,N′-diformylhydrazine 6. Compounds 2 were reacted with 2,5-dimethoxytetrahydrofuran to afford 3-alkyl-4-(1H-pyrrol-1-yl)-4H-1,2,4-triazoles 8.
