38366-03-9

Upstream product

• 91586-03-7 methyl 4,5,6,9,10-pentamethoxyindeno<1,2,3-ij>isoquinoline-8-carboxylate 
• 2103-57-3 2,3,4-trimethoxybenzaldehyde 
• 156050-79-2 N,N-diisopropyl 5'-(E-2-nitroethyl)-2',3,3',4,4'-pentamethoxybiphenyl-2-carboxamide 
• 137993-92-1 2'-N,N-diisopropylcarboxamido-3',4',2,3,4-pentamethoxybiphenyl-5-formaldehyde 
• 137993-93-2 N,N-diisopropyl 5'-(2-aminoethyl)-2',3,3',4,4'-pentamethoxybiphenyl-2-carboxamide 
• 133730-23-1 2-N,N-diisopropylcarboxamido-3,4-dimethoxyphenyl boronic acid 
• 28006-94-2 5-bromo-2,3,4-trimethoxybenzaldehyde 
• 91586-04-8 4,5,6,9,10-Pentamethoxy-indeno[1,2,3-ij]isoquinoline-8-carboxylic acid 
• 38366-08-4 3,4-dihydroimeluteine 

Relevant academic research and scientific papers

Total Syntheses of Azafluoranthene Alkaloids: Rufescine and Imeluteine

Total syntheses of rufescine and imeluteine, azafluoranthene alkaloids isolated from Abuta imene and Abuta rufescens, are detailed and are based on the utilization of the inverse electron demand Diels-Alder reactions of 3-carbomethoxy-2-pyrones for the selective and controlled introduction of oxygenated aromatics.

Ortho and remote metalation - cross coupling strategies. Total synthesis of the naturally occurring fluorenone dengibsinin and the azafluoranthene alkaloid imeluteine

The total synthesis of the naturally occurring fluorenone, dengibsinin (7a), and the azafluoranthene alkaloid, imeluteine (30e), is described. Using combined ortho metalation - cross coupling sequences that terminate in Friedel-Crafts (18b→6d) and remote

Integrated aromatic metalation - cross coupling methodologies. A concise synthesis of the azafluoranthene alkaloid imeluteine

An efficient synthesis of imeluteine (1e) by a combinational metalation (ortho and remote) - cross coupling approach 2 is described.