3837-55-6 Usage
Description
3'-Nitro-4-dimethylaminoazobenzene, also known as NDNB, is a synthetic organic chemical compound characterized by its bright orange-red color. It is primarily recognized for its role as a reagent in analytical chemistry, particularly for the detection and determination of primary and secondary amines. 3'-NITRO-4-DIMETHYLAMINOAZOBENZENE's interaction with primary amines results in the formation of highly colored products, allowing for spectrophotometric detection. Additionally, NDNB has been identified as a carcinogen and mutagen, utilized in laboratory settings to induce mutations in various organisms for research. Given its potential health risks, stringent safety measures are essential when handling NDNB in laboratory environments.
Uses
Used in Analytical Chemistry:
NDNB is employed as a reagent for the detection and determination of primary and secondary amines. Its reaction with primary amines produces highly colored products, enabling spectrophotometric analysis and making it a valuable tool in identifying the presence of these amines in various samples.
Used in Research Applications:
In laboratory settings, NDNB serves as a mutagen, used to induce mutations in various organisms for research purposes. This property is particularly useful in genetic and molecular biology studies, where understanding the effects of mutations on organisms is crucial for advancing scientific knowledge.
Used in Toxicology and Carcinogenicity Studies:
As a known carcinogen and mutagen, NDNB is utilized in toxicology and carcinogenicity studies to investigate the mechanisms of cancer development and the effects of mutagens on biological systems. This helps in the development of strategies for cancer prevention and treatment, as well as in understanding the underlying processes of mutagenesis.
Check Digit Verification of cas no
The CAS Registry Mumber 3837-55-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,8,3 and 7 respectively; the second part has 2 digits, 5 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 3837-55:
(6*3)+(5*8)+(4*3)+(3*7)+(2*5)+(1*5)=106
106 % 10 = 6
So 3837-55-6 is a valid CAS Registry Number.
InChI:InChI=1/C14H14N4O2/c1-17(2)13-8-6-11(7-9-13)15-16-12-4-3-5-14(10-12)18(19)20/h3-10H,1-2H3/b16-15+
3837-55-6Relevant articles and documents
Experimental and theoretical studies of azo derivatives in terms of different donors, acceptors and position isomerism: Synthesis, characterization and a combined electronic absorption, electrochemical and DFT study
Mohan A, Keerthi,Purushothaman, Aiswarya,Janardanan, Deepa,Haridas, Karickal R.
, (2021/10/12)
Eight azo derivatives with two donor groups- diphenylamine and N,N-dimethylphenyl, and four acceptor groups - 3-nitrophenyl, 4-nitrophenyl, 4-phenylcarboxylic acid, and 3-phenylcarboxylic acid, were synthesized and characterized using 1H-NMR an
Synthesis of new azo dyes under phase-transfer catalysis
Chirakadze,Elizbarashvili,Baidoshvili
, p. 1642 - 1645 (2007/10/03)
New azo dyes that do not enter into azo coupling reactions under classical conditions (water solutions, polar organic solvents) were prepared by nontraditional method (in solutions in 1,2-dichloroethane and chloroform and in water emulsions thereof) with the use of phase-transfer catalysts (dibenzo-18-crown-6, benzyltrimethylammonium chloride, sodium 4-dodecylbenzenesulfonate). The azo dyes obtained: 4-(3-nitrophenylazo)-1-bromo-2-methoxynaphthalene, 4-(3-methylphenylazo)-1-bromo-2-methoxynaphthalene, 3-nitrophenylazochrysene, 3-methylphenylazochrysene were produced in high yields and showed good processing properties.
Reactions of Aromatic Nitrocompounds. LXXII. Anionic σ-Complexes of Nitroarenes in the Azocoupling Reaction
Blokhina,Atroshchenko,Gitis,Blokhin,Grudtsyn,Andrianov,Kaminskii
, p. 499 - 501 (2007/10/03)
In reaction of KBH4 with m-dinitrobenzene in acetonitrile a mixture of isomeric anionic σ-complexes is formed. The reaction of the latter with phenyldiazonium tetrafluoroborates RC6H4N2+BF4