383877-50-7

Basic information

• Product Name: (6R)-7-hydroxy-11-nor-methyl-2-[(trimethylsilyl)oxy]-7,8,10,11-tetrahydro-α-bisabolene
• CAS NO: 383877-50-7
• Molecular Weight: 298.541
• Mol File: 383877-50-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (6R)-7-hydroxy-11-nor-methyl-2-[(trimethylsilyl)oxy]-7,8,10,11-tetrahydro-α-bisabolene(CAS DataBase Reference)
• NIST Chemistry Reference: (6R)-7-hydroxy-11-nor-methyl-2-[(trimethylsilyl)oxy]-7,8,10,11-tetrahydro-α-bisabolene(383877-50-7)
• EPA Substance Registry System: (6R)-7-hydroxy-11-nor-methyl-2-[(trimethylsilyl)oxy]-7,8,10,11-tetrahydro-α-bisabolene(383877-50-7)

Safety Data

• Hazardous Substances Data: 383877-50-7(Hazardous Substances Data)

Upstream product

• 383877-46-1 (R)-2-Methyl-5-(2-methyl-oxiranyl)-cyclohex-2-enol 
• 294634-40-5 (5R)-2-methyl-5-(2-methyloxiran-2-yl)cyclohex-2-en-1-one 
• 109-72-8 n-butyllithium 
• 383877-48-3 (5R)-2-methyl-5-(2-methyloxiran-2-yl)-1-[(trimethylsilyl)oxy]cyclohex-2-ene 

Downstream Products

• 383877-54-1 (R)-5-(1-Hydroxy-1-methyl-hexyl)-2-methyl-cyclohex-2-enol 

Relevant articles and documents

Syntheses of a prenylbisabolane diterpene, a natural insecticide from Croton linearis, and of the bisabolane sesquiterpenes (-)-delobanone and (-)-epi-delobanone

An enantioselective first total synthesis of a constituent of Croton linearis, the (-)-7-hydroxy-3,10-prenylbisaboladien-2-one 1, is described as well as the syntheses of the 7-hydroxy-3,10-bisaboladien-2-ones (-)-epi-delobanone (14a) and (-)-delobanone (14b). The model compounds, 7-hydroxy-11-nor-methyl-3-bisabolen-2-one (8a), and 11,15-nor-dimethyl-7-hydroxy-3-bisabolen-2-one (8b), were successfully prepared by opening of the protected carvone epoxide derivative 6 with the appropriate organocuprates. An alternative approach was used for compounds 1 and 14. Thus, these were obtained from homogeranyllithium or homoprenyl Grignard reagent, which reacted successfully with a masked nor-carvone, ketone 11, prepared in four steps from (R)-carvone.