383877-48-3

Upstream product

• 75-77-4 chloro-trimethyl-silane 
• 383877-46-1 (R)-2-Methyl-5-(2-methyl-oxiranyl)-cyclohex-2-enol 
• 294634-40-5 (5R)-2-methyl-5-(2-methyloxiran-2-yl)cyclohex-2-en-1-one 

Downstream Products

• 383877-50-7 (6R)-7-hydroxy-11-nor-methyl-2-[(trimethylsilyl)oxy]-7,8,10,11-tetrahydro-α-bisabolene 
• 383877-56-3 (R)-5-(1-Hydroxy-1-methyl-decyl)-2-methyl-cyclohex-2-enol 
• 383877-54-1 (R)-5-(1-Hydroxy-1-methyl-hexyl)-2-methyl-cyclohex-2-enol 
• 383877-52-9 2-((R)-4-Methyl-5-trimethylsilanyloxy-cyclohex-3-enyl)-undecan-2-ol 
• 84453-40-7 (+)-bottrospicatol 
• 84453-40-7 (+)-isobottrospicatol 

Relevant academic research and scientific papers

Syntheses of a prenylbisabolane diterpene, a natural insecticide from Croton linearis, and of the bisabolane sesquiterpenes (-)-delobanone and (-)-epi-delobanone

An enantioselective first total synthesis of a constituent of Croton linearis, the (-)-7-hydroxy-3,10-prenylbisaboladien-2-one 1, is described as well as the syntheses of the 7-hydroxy-3,10-bisaboladien-2-ones (-)-epi-delobanone (14a) and (-)-delobanone (14b). The model compounds, 7-hydroxy-11-nor-methyl-3-bisabolen-2-one (8a), and 11,15-nor-dimethyl-7-hydroxy-3-bisabolen-2-one (8b), were successfully prepared by opening of the protected carvone epoxide derivative 6 with the appropriate organocuprates. An alternative approach was used for compounds 1 and 14. Thus, these were obtained from homogeranyllithium or homoprenyl Grignard reagent, which reacted successfully with a masked nor-carvone, ketone 11, prepared in four steps from (R)-carvone.