383883-64-5

Upstream product

• 104-94-9 4-methoxy-aniline 
• 383883-66-7 (+)-(3R,4R)-4-formyl-3-methoxy-1-(p-tolyl)-2-azetidinone 

Downstream Products

• 383883-65-6 2-(3-methoxy-4-oxo-1-p-tolyl-azetidin-2-yl)-1-(4-methoxy-phenyl)-2,3-dihydro-1H-pyridin-4-one 
• 383883-62-3 2-(3-methoxy-4-oxo-1-p-tolyl-azetidin-2-yl)-1-(4-methoxy-phenyl)-2,3-dihydro-1H-pyridin-4-one 
• 604788-97-8 (3R,4S)-4-[(2S,4R)-4-(tert-Butyl-dimethyl-silanyloxy)-1-(4-methoxy-phenyl)-piperidin-2-yl]-3-methoxy-1-p-tolyl-azetidin-2-one 
• 604788-98-9 (3R,4S)-4-[(2S,4R)-4-(tert-Butyl-dimethyl-silanyloxy)-piperidin-2-yl]-3-methoxy-1-p-tolyl-azetidin-2-one 
• 604788-95-6 (S)-2-((2S,3R)-3-Methoxy-4-oxo-1-p-tolyl-azetidin-2-yl)-1-(4-methoxy-phenyl)-piperidin-4-one 
• 604788-96-7 (3R,4S)-4-[(2S,4R)-4-Hydroxy-1-(4-methoxy-phenyl)-piperidin-2-yl]-3-methoxy-1-p-tolyl-azetidin-2-one 
• 383883-57-6 (1S,2R,7R,8aS)-7-(tert-Butyl-dimethyl-silanyloxy)-2-methoxy-1-p-tolylamino-hexahydro-indolizin-3-one 

Relevant academic research and scientific papers

Dual behavior of 2-azetidinone-tethered arylimines as azadienophiles or azadienes. Application to the asymmetric synthesis of indolizidine-type systems

The first methodology to prepare indolizidine systems directly from β-lactams has been developed. This process involves the amide bond cleavage of the β-lactam ring in the aza Diels-Alder cycloadducts with concomitant cyclization. Indolizidinone precursor