384338-21-0 Usage
Description
N-Benzyl-3-hydroxy-4-Methyl-piperidiniuM Toluene-4-sulfonate is a quaternary ammonium salt featuring an aromatic toluene sulfonate group and a piperidine ring structure. This chemical compound is characterized by a positively charged nitrogen atom and is known for its versatility in various chemical processes.
Uses
Used in Organic Synthesis:
N-Benzyl-3-hydroxy-4-Methyl-piperidiniuM Toluene-4-sulfonate is used as a phase-transfer catalyst to facilitate the transfer of reactants between different phases, such as between aqueous and organic solvents. This enhances the efficiency and speed of reactions in organic synthesis.
Used in Pharmaceutical Synthesis:
In the pharmaceutical industry, N-Benzyl-3-hydroxy-4-Methyl-piperidiniuM Toluene-4-sulfonate is utilized in the synthesis of various drugs. Its unique structure and properties make it a valuable component in creating new and effective medications.
Used in Agrochemical Production:
N-Benzyl-3-hydroxy-4-Methyl-piperidiniuM Toluene-4-sulfonate also plays a role in the production of agrochemicals, contributing to the development of pesticides and other agricultural products that are essential for maintaining crop health and productivity.
Used in Dye and Pigment Manufacturing:
N-Benzyl-3-hydroxy-4-Methyl-piperidiniuM Toluene-4-sulfonate is employed in the manufacturing of dyes and pigments, where its chemical properties contribute to the creation of vibrant colors and stable compounds for various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 384338-21-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,8,4,3,3 and 8 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 384338-21:
(8*3)+(7*8)+(6*4)+(5*3)+(4*3)+(3*8)+(2*2)+(1*1)=160
160 % 10 = 0
So 384338-21-0 is a valid CAS Registry Number.
384338-21-0Relevant articles and documents
Development of a scaleable route for the production of cis-N-benzyl-3-methylamino-4-methylpiperidine
Brown Ripin, David H.,Abele, Stefan,Cai, Weiling,Blumenkopf, Todd,Casavant, Jeffrey M.,Doty, Jonathan L.,Flanagan, Mark,Koecher, Christian,Laue, Klaus W.,McCarthy, Keith,Meltz, Cliff,Munchhoff, Mike,Pouwer, Kees,Shah, Bharat,Sun, Jianmin,Teixeira, John,Vries, Ton,Whipple, David A.,Wilcox, Glenn
, p. 115 - 120 (2013/09/05)
The synthesis of cis-N-benzyl-3-methylamino-4-methylpiperidine (5) via hydroboration of tetrahydropyridine 3 followed by oxidation and reductive amination was optimized and scaled up to produce 10-kg quantities of product. Three routes to 3 were identified, and the reduction of pyridinium salt 7 was selected as the most preferable to run on-scale. The hydroboration and oxidative workup were carefully studied to optimize throughput on that transformation, as was the reductive amination.
