38446-98-9

Upstream product

• 110-89-4 piperidine 
• 110-86-1 pyridine 
• 14371-10-9 (E)-3-phenylpropenal 
• 141-82-2 malonic acid 
• 676551-01-2 2-((Z)-3-Phenyl-allylidene)-malonic acid 
• 34271-87-9 3-(2-carboxy-4-phenyl-3-styryl-cyclobutyl)-acrylic acid 
• 66838-71-9 1,1-Dichlor-5-phenyl-pentadien-(1,3)-on-⁽⁵⁾ 
• 104-55-2 3-phenyl-propenal 
• 927-80-0 1-ethoxyacetylene 
• 67-56-1 methanol 
• 1552-94-9 (2Z,4E)-5-phenylpenta-2,4-dienoic acid 
• 67-66-3 chloroform 
• 13466-40-5 5-phenylpenta-2,4-dienal 
• 105-53-3 diethyl malonate 

Downstream Products

• 1515-78-2 buta-1,3-dien-1-ylbenzene 
• 2270-20-4 5-Phenylpentanoic acid 
• 40926-86-1 5-phenyl-penta-2,4-dienoyl chloride 
• 91062-95-2 2-bromo-5-phenyl-penta-2,4-dienoic acid 
• 34271-87-9 3-(2-carboxy-4-phenyl-3-styryl-cyclobutyl)-acrylic acid 
• 872281-94-2 5-phenyl-penta-2,4-dienoic acid allyl ester 
• 72071-71-7 3,5-Bis-hydroxyamino-5-phenyl-pentanoic acid 
• 102028-94-4 2-methylsulfanyl-6-(4-phenyl-buta-1,3-dienyl)-benzothiazole 
• 886-65-7 trans,trans-1,4-Diphenyl-1,3-butadiene 
• 17329-15-6 1,6-diphenyl-1,3,5-hexatriene 
• 36288-11-6 (1E,3E,5E)-1-(4-chlorophenyl)-6-phenyl-1,3,5-hexatriene 
• 1206103-30-1 (1E,3E,5E)-1-phenyl-6-(4-trifluoromethylphenyl)-1,3,5-hexatriene 
• 100393-63-3 N-(5-phenyl-penta-2,4-dienoyl)-glycine 

Relevant academic research and scientific papers

Photo-Promoted Decarboxylative Alkylation of α, β-Unsaturated Carboxylic Acids with ICH2CN for the Synthesis of β, γ-Unsaturated Nitriles

An efficient, catalyst/photocatalyst-free, and cost-effective methodology for the decarboxylative alkylation of α,β-unsaturated carboxylic acids to synthesize β,γ-unsaturated nitriles has been developed. The reaction proceeded in an environmentally benign atmosphere of blue light-emitting diode irradiation with K2CO3 and water at room temperature. The methodology worked for a wide range of substrates (22 examples) with up to 83% yield. The protocol is also compatible for gram-scale synthesis.

Essential structural features of (2Z,4E)-5-phenylpenta-2,4-dienoic acid for inhibition of root gravitropism

Previously, we found (2Z,4E)-5-phenylpenta-2,4-dienoic acid (ku-76) to be a selective inhibitor of root gravitropic bending of lettuce radicles at 5 μM, with no concomitant growth inhibition. Here, we describe a structure-activity relationship study of ku

Enantioselective Redox-Divergent Chiral Phosphoric Acid Catalyzed Quinone Diels–Alder Reactions

An efficient enantioselective construction of tetrahydronaphthalene-1,4-diones as well as dihydronaphthalene-1,4-diols by a chiral phosphoric acid catalyzed quinone Diels–Alder reaction with dienecarbamates is reported. The nature of the protecting group on the diene is key to the success of achieving high enantioselectivity. The divergent “redox” selectivity is controlled by using an adequate amount of quinones. Reversible redox switching without erosion of enantioselectivity was possible from individual redox isomers.

Reaction of 5-phenylpenta-2,4-dienoic acid with benzene in trifluoromethanesulfonic acid

The reaction of 5-phenylpenta-2,4-dienoic acid with benzene in CF3SO3H, depending on the reaction conditions, gives three products, namely, 5,5-diphenylpent-2-enoic acid and tetralone and indanone derivatives. These carbocyclic compo

Iron-Catalyzed Reactions of 2-Pyridone Derivatives: 1,6-Addition and Formal Ring Opening/Cross Coupling

In the presence of simple iron salts, 2-pyridone derivatives react with Grignard reagents under mild conditions to give the corresponding 1,6-addition products; if the reaction medium is supplemented with an aprotic dipolar cosolvent after the actual addition step, the intermediates primarily formed succumb to ring opening, giving rise to non-thermodynamic Z,E-configured dienoic acid amide derivatives which are difficult to make otherwise. Control experiments as well as the isolation and crystallographic characterization of a (tricarbonyl)iron pyridone complex suggest that the active iron catalyst generated in situ exhibits high affinity to the polarized diene system embedded into the heterocyclic ring system of the substrates, which likely serves as the actual recognition element.

Cis-cinnamic acid analogue, gravitropism modifier (by machine translation)

[Problem] cinnamic acid or cinnamic acid analogue comprising adjusting agent gravitropism cis. [Solution] cinnamic acid and/or cinnamic acid as an active ingredient to adjust gravitropism cis edge agents, cinnamic acid edge is, for example obtained by reacting compounds of the following formula. (In the formula, R is a phenyl group. )Figure 6 [drawing] (by machine translation)

Ni-Catalyzed Site-Selective Dicarboxylation of 1,3-Dienes with CO2

A site-selective catalytic incorporation of multiple CO2 molecules into 1,3-dienes en route to adipic acids is described. This protocol is characterized by its mild conditions, excellent chemo- and regioselectivity and ease of execution under CO2 (1 atm), including the use of bulk butadiene and/or isoprene feedstocks.

Enantioselective Synthesis of N?H-Free 1,5-Benzothiazepines

An enantioselective sulfa-Michael-cyclization reaction was developed for the synthesis of 1,5-benzothiazepines with versatile pharmacological activities. The reaction between 2-aminothiophenol and α,β-unsaturated pyrazoleamides gave direct access to N?H-free 1,5-benzothiazepines in the presence of a chiral N,N′-dioxide/Yb(OTf)3complex. Excellent enantioselectivities (up to 96 % ee) and high yields (up to 99 %) were obtained for a broad range of substrates under mild reaction conditions. This method provided a facile approach to the antidepressant drug (R)-(?)-Thiazesim.

Photoinduced, Copper-Promoted Regio- and Stereoselective Decarboxylative Alkylation of α,β-Unsaturated Acids with Alkyl Iodides

The first example of UV light-induced, copper-catalyzed regio- and stereoselective decarboxylative coupling of α,β-unsaturated acids with alkyl iodides was reported. Under standard conditions, the 1°, 2°, and 3° alkyl iodides proceeded smoothly with the E-selective alkenes obtained in uniformly good yields and high stereoselectivities.

CIS CINNAMIC ACID ANALOG AND GRAVITROPISM MODIFIER

PROBLEM TO BE SOLVED: To provide a gravitropism modifier having effects on creeping property of plants or sugar content of fruits. SOLUTION: There is provided a gravitropism modifier containing cis cinnamic acid and/or a cinnamic acid analog represented by the formula (1) as active ingredients. (1), where A is cyclic hydrocarbon which may have a substituent, X is a bound or a C1 to 5 substituted or unsubstituted hydrocarbon chain, R1 is H, a hydroxyl group, an alkali earth metal salt or the like, R2 is a bond or a C1 to 5 substituted or unsubstituted hydrocarbon chain and R3 and R4 are H or together form C5 to 8 cyclic hydrocarbon. SELECTED DRAWING: Figure 6 COPYRIGHT: (C)2016,JPOandINPIT