38470-63-2

Upstream product

• 487-89-8 Indole-3-carboxaldehyde 
• 98-86-2 acetophenone 
• 13993-17-4 3-(1H-indol-3-yl)-1-phenylpropan-1-one 
• 120-72-9 indole 
• 768-03-6 Phenyl vinyl ketone 
• 20913-05-7 (Benzoylmethylene)triphenylphosphorane 

Downstream Products

• 27664-09-1 (E)-3-(1-methyl-1H-indol-3-yl)-1-phenylprop-2-en-1-one 
• 140472-63-5 5,5-dimethyl-4-(1'-methylindol-3'yl)-2-phenyl-1-pyrroline 
• 140472-62-4 5,5-dimethyl-4-(1'-methylindol-3'-yl)-2-phenyl-1-pyrroline 1-oxide 
• 140472-56-6 4-methyl-3-(1'-methylindol-3'-yl)-4-nitro-1-phenylpentan-1-one 
• 1018817-79-2 3-(2-methyl-5-phenyl-3,4-dihydro-2H-pyrazol-3-yl)-1H-indole 
• 1330579-01-5 (E)-3-(1H-indol-3-yl)-1,5-diphenylpent-4-en-1-one 
• 69022-92-0 5-(1H-indol-3-yl)-3-(phenyl)-4,5-dihydroisoxazoline 
• 119549-92-7 3-(3-indolyl)-3-(1,2,4-triazol-1-yl)-1-phenyl-propan-1-one 
• 119550-01-5 3-(3-indolyl)-3-(1,2,4-triazol-1-yl)-1-phenylpropan-1-ol 
• 13993-17-4 3-(1H-indol-3-yl)-1-phenylpropan-1-one 
• 1233334-60-5 4-(1H-indol-3-yl)-7,7-dimethyl-2-phenyl-4,6,7,8-tetrahydroquinolin-5(1H)-one 

Relevant academic research and scientific papers

Synthesis and evaluation of chalcone derivatives as novel sunscreen agent

Ultraviolet (UV) irradiation is a serious problem for skin health thus the interest in the research to develop sunscreen agent has been increasing. Chalcone is a promising compound to be developed as its chromophore absorbs in the UV region. Therefore, in

A new method for the synthesis of chalcone derivatives promoted by PPh3/I2under non-alkaline conditions

A straightforward and general method has been developed for the synthesis of chalcone derivatives by a Claisen-Schmidt reaction in the presence of PPh3/I2 in 1,4-dioxane under reflux temperatures. With the condensation of the aromatic ketone and aldehyde occurring at non-strongly alkaline conditions, our proposed method significantly expands the range of applicable substrates, especially for groups that are unstable under alkaline conditions.

Synthesis and carbonic anhydrase inhibition studies of sulfonamide based indole-1,2,3-triazole chalcone hybrids

Sulfonamide is one of the most promising classes of classical carbonic anhydrase (CA, EC 4.2.1.1) inhibitors. A novel series of indolylchalcones incorporating benzenesulfonamide-1,2,3-triazole (6a-q) has been synthesized by click chemistry reaction and in

Alpha,beta-unsaturated ketone derivatives, preparation method of derivatives and application of derivatives as medicines

The invention relates to the technical field of medicine, and proposes alpha,beta-unsaturated ketone derivatives and a preparation method thereof. The derivatives have a structural general formula represented by a formula I shown in the specification, whe

Synthesis, docking, and evaluation of novel thiazoles for potent antidiabetic activity

In this study, a series of novel substituted pyrazoles containing indole and thiazole motifs were synthesized and evaluated for their antihyperglycemic activity against α-amylase and α-glucosidase enzymes. Among them, 2-(5-(1H-indol-3-yl)-3-phenyl-1H-pyra

Synthesis, Characterisation, Molecular Docking, Anti-microbial and Anti-diabetic Screening of Substituted 4-indolylphenyl-6-arylpyrimidine-2-imine Derivatives

The purpose of the research is to synthesise a novel series of (E)-2-(4-(1H-indol-3-yl)-6-p-substituted phenylpyrimidin-2-yl)dimethylguanidine derivatives since 3-(1H-indol-3-yl)-1-p-substituted phenylprop-2-en-1-one and evaluate their molecular docking s

Synthesis and antioxidant activity of a new class of pyrazolyl indoles, thiazolyl pyrazolyl indoles

A new class of bis and tris heterocycles–pyrazolyl indoles and thiazolyl pyrazolyl indoles were prepared from the Michael acceptor (E)-3-(1H-indol-3-yl)-1-arylprop-2-en-1-ones by ultrasound irradiation technique and tested for antioxidant activity. The th

Preheated fly-ash catalyzed aldol condensation: Efficient synthesis of chalcones and antimicrobial activities of some 3-thienyl chalcones

In the present study we have prepared a series of some chalcones using solvent - free Aldol - condensation by microwave irradiation. The yields of the ketones are more than 60%. The synthesised chalcones were characterized by their analytical, physical and spectral data. The antimicrobial activities of substituted styryl 3-thienyl ketones have been studied using Bauer-Kirby method.

An efficient method for the synthesis of isoxazolines under microwave irradiation and solvent-free conditions

A facile method for the synthesis of new isoxazoline derivatives are being reported starting from substituted 1-(1H-indol-3-yl)-3-(substituted aryl)-prop-1-en-3-ones and hydroxylamine hydrochloride under solvent free conditions and microwave irradiation.

Fly-ash:H2SO4 catalyzed solvent free efficient synthesis of some aryl chalcones under microwave irradiation

Some 2E aryl chalcones have been synthesized using greener catalyst Fly-ash:H2SO4 assisted solvent free environmentally benign Crossed-Aldol reaction. The yields of chalcones are more than 90%. The synthesized chalcones are characterized by their physical constants and spectral data.