38476-40-3

Basic information

• Product Name: Benzoic acid, 2-(hydroxyamino)-, ethyl ester
• Synonyms: Benzoic acid,2-(hydroxyamino)-,ethyl ester;Carbethoxyphenylhydroxylamine;2-Hydroxylamino-benzoesaeure-aethylester;2-hydroxyamino-benzoic acid ethyl ester;o-Hydroxylamino-benzoesaeure-ethylester;N-(2-Ethoxycarbonyl-phenyl)-hydroxylamin;2-Hydroxyamino-benzoesaeure-aethylester
• CAS NO: 38476-40-3
• Molecular Formula: C9H11NO3
• Molecular Weight: 181.191
• Mol File: 38476-40-3.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 315.8±44.0 °C(Predicted)
• Density: 1?+-.0.06 g/cm3(Predicted)
• CAS DataBase Reference: Benzoic acid, 2-(hydroxyamino)-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2-(hydroxyamino)-, ethyl ester(38476-40-3)
• EPA Substance Registry System: Benzoic acid, 2-(hydroxyamino)-, ethyl ester(38476-40-3)

Safety Data

• Hazardous Substances Data: 38476-40-3(Hazardous Substances Data)

Upstream product

• 610-34-4 ethyl 2-nitrobenzoate 
• 87-25-2 2-ethoxycarbonylaniline 

Downstream Products

• 690959-87-6 ethyl 2-(propoxyamino)benzoate 
• 57892-27-0 ethyl 2-nitrosobenzoate 

Relevant articles and documents

Selective Photoinduced Reduction of Nitroarenes to N-Arylhydroxylamines

We report the selective photoinduced reduction of nitroarenes to N-arylhydroxylamines. The present methodology facilitates this transformation in the absence of catalyst or additives and uses only light and methylhydrazine. This noncatalytic photoinduced transformation proceeds with a broad scope, excellent functional-group tolerance, and high yields. The potential of this protocol reflects on the selective and straightforward conversion of two general antibiotics, azomycin and chloramphenicol, to the bioactive hydroxylamine species.

PROCESS FOR PREPARING SUBSTITUTED N-PHENYLHYDROXYLAMINES

The present invention relates to a process for the preparation of 2-[[[1-(4-chlorophenyl)-1H-pyrazol-3-yl]oxy]methyl] phenyl]-hydroxylamine from the correspondingly substituted nitrobenzene compound.

Anti-infective agents

Compounds having the formula are hepatitis C(HCV) polymerase inhibitors. Also disclosed are a composition and method for inhibiting hepatitis C(HCV) polymerase, processes for making the compounds, and synthetic intermediates employed in the processes.