610-34-4

Basic information

• Product Name: ETHYL 2-NITROBENZOATE
• Synonyms: RARECHEM AL BI 0186;LABOTEST-BB LT01148447;ETHYL-O-NITROBENZOATE;ETHYL 2-NITROBENZOATE;Benzoic acid, o-nitro-, ethyl ester;2-Nitrobenzoic acid ethyl ester
• CAS NO: 610-34-4
• Molecular Formula: C₉H₉NO₄
• Molecular Weight: 195.17
• EINECS: 210-220-0
• Product Categories: Aromatic Esters
• Mol File: 610-34-4.mol
• Article Data: 29

Chemical Properties

• Melting Point: 26-30°C
• Boiling Point: 172-174°C 18mm
• Flash Point: 172-174°C/18mm
• Appearance: /
• Density: 1.3544 (rough estimate)
• Vapor Pressure: 0.00523mmHg at 25°C
• Refractive Index: 1.5700 (estimate)
• Merck: 14,3832
• BRN: 2050729
• CAS DataBase Reference: ETHYL 2-NITROBENZOATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL 2-NITROBENZOATE(610-34-4)
• EPA Substance Registry System: ETHYL 2-NITROBENZOATE(610-34-4)

Safety Data

• Statements: 20/21/22
• Safety Statements: 23-36/37/39
• Hazardous Substances Data: 610-34-4(Hazardous Substances Data)

Usage

General Description

Ethyl 2-nitrobenzoate, also known as ethyl o-nitrobenzoate, is a chemical compound with the molecular formula C9H9NO4. It is a yellow crystalline solid with a melting point of 57-59°C and a boiling point of 279-280°C. Ethyl 2-nitrobenzoate is commonly used in the field of organic chemistry as a building block to synthesize various pharmaceuticals, dyes, and other organic compounds. It is known to react violently with strong oxidizing agents and should be handled with care. The compound is also a potential environmental hazard and should be disposed of properly according to local regulations to prevent pollution.

InChI:InChI=1/C9H9NO4/c1-2-14-9(11)7-5-3-4-6-8(7)10(12)13/h3-6H,2H2,1H3

Upstream product

• 64-17-5 ethanol 
• 552-16-9 ortho-nitrobenzoic acid 
• 31042-59-8 phenyl 2-nitrobenzoate 
• 93-89-0 benzoic acid ethyl ester 
• 7697-37-2 nitric acid 
• 141-52-6 sodium ethanolate 
• 75-03-6 ethyl iodide 
• 201230-82-2 carbon monoxide 
• 609-73-4 o-nitroiodobenzene 
• 577-19-5 2-nitrophenyl bromide 
• 606-27-9 methyl 2-nitrobenzoate 
• 610-14-0 2-nitrobenzyl chloride 
• 845868-26-0 ethyl 3-bromo-3-nitropropenoate 
• 1165952-91-9 cyclohexa-1,3-diene 

Downstream Products

• 57892-27-0 ethyl 2-nitrosobenzoate 
• 38476-40-3 ethyl 2-(hydroxyamino)benzoate 
• 27542-75-2 2-nitro-benzoic acid menthyl ester 
• 87-25-2 2-ethoxycarbonylaniline 
• 83725-81-9 C₈H₅N₃O₃S 
• 1429183-39-0 2-((2-(2-methyl-5-nitro-1H-imidazole-1-yl)ethyl)thio)-5-(2-nitrophenyl)-1,3,4-oxadiazole 
• 1656990-87-2 ethyl 2-[¹⁸F]fluorobenzoate 
• 66924-63-8 2,2-dichloro-1-(2-nitrophenyl)ethan-1-one 
• 552-16-9 ortho-nitrobenzoic acid 
• 1371604-29-3 C₁₅H₁₃N₃O₃ 

Relevant articles and documents

Nitration of deactivated aromatic compounds via mechanochemical reaction

A variety of deactivated arenes were nitrated to their corresponding nitro derivatives in excellent yields under high-speed ball milling condition using Fe(NO3)3·9H2O/P2O5 as nitrating reagent. A radical involved mechanism was proposed for this facial, eco-friendly, safe, and effective nitration reaction.

PROCESS FOR THE PREPARATION OF QUINOLONE BASED COMPOUNDS

The present invention relates to an improved process for the preparation of quinolone based compounds of general formula (I) using intermediate compound of general formula (XII). Invention also provides an improved process for the preparation of compound of formula (I-a) using intermediate compound of formula (XII-a) and some novel impurities generated during process. Compounds prepared using this process can be used to treat anemia.

Synthesis, spectral analysis and antibacterial evaluation of 5-substituted-1,3,4-oxadiazol-2-yl 4-(4-methylpiperidin-1-ylsulfonyl)benzyl sulfides

Owing to valuable biological activities of 1,3,4-oxadiazole, sulfamoyl and piperidine functionalities, some new 1-(4-{[(5-substituted-1,3,4-oxadiazol-2-yl) thio]methyl}benzene sulfonyl)-4-methylpiperidine (6a-o) derivatives have been introduced. The target molecules were synthesized from different aralkyl/aryl carboxylic acids, 1a-o, through a series of steps. First the compounds, 1a-o, were converted to heterocyclic 1,3,4-oxadiazole nucleophiles, 4a-o. Second an electrophile as 1-(4-bromomethylbenzenesulfonyl)-4-methylpiperidine (5) was synthesized from 4-methylpiperidine. Finally the target compounds, 6a-o, were prepared by reacting 4a-o with 5 in DMF and LiH. The final compounds were structurally elucidated by spectral data of IR, 1H-NMR and EI-MS. All the compounds were screened for their antibacterial evaluation and found to exhibit valuable results.