57892-27-0Relevant articles and documents
Azobenzene-benzoylphenylureas as photoswitchable chitin synthesis inhibitors
Tian, Xue,Zhang, Chao,Xu, Qi,Li, Zhong,Shao, Xusheng
, p. 3320 - 3323 (2017/04/21)
Benzoylphenylureas (BPUs) are used as synthetic insect growth regulators for inhibiting chitin synthesis. Merging insecticidal BPUs with photoswitchable azobenzene generated photoresponsive chitin synthesis inhibitors. A prepared azobenzene-benzoylphenylurea can be activated upon irradiation with UV light, and shows 6-fold and 2-fold activity difference to armyworm (Mythimna separata) and German cockroach (Blattella germanica) sulfonylurea receptors, respectively. This is the first example of a photoswitchable BPU insecticide. The generation of such a photoresponsive BPU insecticide allows for modulation of the insecticidal activity by light, and may facilitate the spatiotemporal control over the sulfonylurea receptor and the mechanistic study of this kind of insecticide.
Photoswitchable thioureas for the external manipulation of catalytic activity
Osorio-Planes, Laura,Rodriguez-Escrich, Carles,Pericas, Miquel A.
supporting information, p. 1704 - 1707 (2014/04/17)
A series of azobenzene-based thiourea catalysts have been developed with the aim of achieving control over the catalytic activity by the use of light. The conceptual design of these systems relies on the inactivation by means of intramolecular hydrogen bonding, only likely to take place in one of their isomeric forms. After fine structure modulation of the catalyst a substantial difference in activity has been observed between the irradiated and the nonirradiated reaction. Furthermore, the system allowed in situ manipulation of the catalyst activity during the course of a given experiment.