384820-79-5

Upstream product

• 104-86-9 4-chlorobenzylamine 
• 384821-04-9 4-chloro-6-methoxy-8-methylquinoline 
• 102-50-1 2-methyl-4-methoxyaniline 
• 384821-02-7 4-hydroxy-6-methoxy-8-methylquinoline 
• 384821-00-5 4-hydroxy-6-methoxy-8-methyl-quinoline-3-carboxylic acid 
• 384820-97-7 diethyl 2-((4-methoxy-2-methylphenylamino)methylene)malonate 
• 384820-98-8 ethyl 4-hydroxy-6-methoxy-8-methylquinoline-3-carboxylate 

Relevant academic research and scientific papers

Synthesis and antibacterial activity of 5- and 6-hydroxy substituted 4-aminoquinolines and derivatives

The synthesis and antimicrobial activity of 4-amino-8-methylquinolines 8, 11 substituted with a hydroxy- or methoxy-group at 5- and at 6-position have been investigated. The title compounds could be prepared by a six-step procedure according to the literature starting from commercially available anilines 1. The novel 4-aminoquinolines 8,11 exhibited slight antibacterial activity against Gram-positive and Gram-negative bacteria.