38510-79-1

Upstream product

• 558-37-2 tert-butylethylene 
• 5394-63-8 2,2,6-trimethyl-4H-1,3-dioxin-4-one 
• 51036-60-3 3-(tert-butyl)cyclohex-2-en-1-ol 
• 92974-02-2 anti-7-tert-butylbicyclo<2.2.1>heptane-2,3-dione, (Z)-monotosylhydrazone 
• 92973-98-3 anti-7-tert-butylbicyclo<2.2.1>heptane-2,3-dione 
• 92973-86-9 anti-7-tert-butylbicyclo<2.2.1>heptan-2-one 
• 81360-51-2 trans-3-hydroxy-6-tert-butyl-1-(trimethylsiloxy)-1-cyclohexene 
• 6310-21-0 2-(1,1-dimethylethyl)-benzenamine 
• 2944-48-1 2-tert-butylanisole 

Downstream Products

• 109451-96-9 1-(4-tert-butyl-3-oxo-cyclohexyl)-1-methyl-piperidinium; iodide 
• 101107-56-6 2-tert-butyl-5-piperidino-cyclohexanone 

Relevant academic research and scientific papers

Tuning of α-Silyl Carbocation Reactivity into Enone Transposition: Application to the Synthesis of Peribysin D, E-Volkendousin, and E-Guggulsterone

A reliable method for enone transposition has been developed with the help of silyl group masking. Enantio-switching, substituent shuffling, and Z-selectivity are the highlights of the method. The developed method was applied for the first total synthesis of peribysin D along with its structural revision. Formal synthesis of E-guggulsterone and E-volkendousin was also claimed using a short sequence.

THE ACID INDUCED DECOMPOSITION OF 7-SUBSTITUTED 3-DIAZO-2-NORBORNANONES.THE STRUCTURES OF THE PRODUCTS AND THEIR DISTRIBUTION

Introduction of a syn-7 isopropyl or t-butyl substituent in 3-diazo-2-norbornanone results in both endo and exo protonation in aqueous acid and a marked decrease in α-ketol and increase in tricyclanone formation.