2944-48-1

Basic information

• Product Name: 2-(2-Methoxy-phenyl)-propan-2-ol
• Synonyms: 2-(2-Methoxy-phenyl)-propan-2-ol;1-tert-Butyl-2-methoxy-benzene
• CAS NO: 2944-48-1
• Molecular Formula: C₁₁H₁₆O
• Molecular Weight: 166.21696
• EINECS: 253-174-7
• Mol File: 2944-48-1.mol
• Article Data: 26

Chemical Properties

• Boiling Point: 225.4°Cat760mmHg
• Flash Point: 91.5°C
• Appearance: /
• Density: 0.911g/cm³
• CAS DataBase Reference: 2-(2-Methoxy-phenyl)-propan-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(2-Methoxy-phenyl)-propan-2-ol(2944-48-1)
• EPA Substance Registry System: 2-(2-Methoxy-phenyl)-propan-2-ol(2944-48-1)

Safety Data

• Hazardous Substances Data: 2944-48-1(Hazardous Substances Data)

Usage

General Description

2-(2-Methoxy-phenyl)-propan-2-ol, also known as guaiacol glyceryl ether, is a chemical compound with the molecular formula C10H14O2. It is an organic compound that contains a benzene ring with a methoxy group attached to it. This chemical is commonly used in various industrial applications, including as a flavoring agent in the food industry and as a fragrance ingredient in the cosmetic and personal care products. It also has potential therapeutic applications, such as in the treatment of coughs and respiratory conditions. Guaiacol glyceryl ether is considered to be relatively safe for use, but like all chemicals, it should be handled and used with appropriate caution and following safety protocols.

Upstream product

• 74-87-3 methylene chloride 
• 88-18-6 2-tert-Butylphenol 
• 5396-38-3 1-(tert-butyl)-4-methoxybenzene 
• 33733-83-4 3-tert-butyl-1-methoxybenzene 
• 507-20-0 tertiary butyl chloride 
• 100-66-3 methoxybenzene 
• 507-19-7 t-butyl bromide 
• 186581-53-3 diazomethane 
• 578-57-4 2-bromoanisole 
• 677-22-5 tert-butylmagnesium chloride 
• 594-19-4 tert.-butyl lithium 
• 144-55-8 sodium hydrogencarbonate 
• 109-72-8 n-butyllithium 
• 50-00-0 formaldehyd 

Downstream Products

• 6609-56-9 2-methoxy-benzonitrile 
• 68527-72-0 2-tert-butyl-1-cyanobenzene 
• 66737-90-4 3-tert-butyl-4-methoxybenzonitrile 
• 60772-81-8 3-tert-butyl-2-methoxybenzoic acid 
• 14804-34-3 3-tert-butyl-4-methoxybromobenzene 
• 88-18-6 2-tert-Butylphenol 
• 1417537-04-2 [2-methyl-4-phenyl-5-methoxy-6-tert-butyl-1H-inden-1-yl]-[2-methyl-4-(3,5-di-tertbutylphenyl)-7-methoxy-1H-inden-1-yl]dimethylsilane 
• 1417536-99-2 (2-methyl-4-phenyl-5-methoxy-6-tert-butyl-1H-inden-1-yl)[2,7-dimethyl-4-(3,5-di-tert-butylphenyl)-1H-inden-1-yl]dimethylsilane 
• 1417537-00-8 (2-methyl-4-phenyl-5-methoxy-6-tert-butyl-1H-inden-1-yl)[2,4-dimethyl-7-(3,5-di-tert-butylphenyl)-1H-inden-1-yl]dimethyl silane 
• 1417536-85-6 [6-tert-butyl-4-(3,5-di-tert-butylphenyl)-2-methyl-1H-inden-1-yl]-(6-tert-butyl-5-methoxy-2-methyl-4-phenyl-1H-inden-1-yl)dimethylsilane 
• 1417536-81-2 (6-tert-butyl-5-methoxy-2-methyl-4-phenyl-1H-inden-1-yl)[4-(4-tert-butylphenyl)-2-methyl-1H-inden-1-yl] dimethylsilane 
• 1417536-78-7 (6-tert-butyl-5-methoxy-2-methyl-4-phenyl-1H-inden-1-yl)(chloro)dimethylsilane 
• 1417536-80-1 (6-tert-butyl-5-methoxy-2-methyl-4-phenyl-1H-inden-1-yl)-(6-tert-butyl-2-methyl-4-phenyl-1H-inden-1-yl)dimethylsilane 
• 1417537-12-2 [6-tert-Butyl-4-(3,5-di-tert-butylphenyl)-5-methoxy-2-methyl-1H-inden-1-yl] [4-(4-tert-butylphenyl)-2-methyl-1H-inden-1-yl]dimethylsilane 

Relevant articles and documents

Catalysis by 12-Heteropolymolybdic Acid. II. Friedel-Crafts-type Reaction of Aromatic Compounds

12-Heteropolymolybdic acid, a heteropolyacid of Keggin-structure, behaves as an effective catalyst of the Friedel-Crafts-type reactions for aromatic compounds, such as alkylation by benzyl chloride and t-butyl chloride, acylation by acetyl chloride, and sulfonylation by tosyl chloride.The catalyst mainly gives para-substiuted products for phenol and anisole.The reactions proceed via carbocation-generation mechanism brought about by the strong Broensted acid.

An N-heterocyclic carbene-based nickel catalyst for the Kumada–Tamao–Corriu coupling of aryl bromides and tertiary alkyl Grignard reagents

In this study, nickel-catalyzed coupling reactions between arylhalides and tert-alkyl Grignard reagents were developed. Our original bicyclic NHC ligands reduced the formation of isomerized products, and we found that NMP as a co-solvent suppressed the reduction process. Under the optimal conditions we developed, the catalyst loading was lowered to 0.5?mol?%, and catalyst loading using ortho-substituted aryl bromides was also applicable at the level of 2.0?mol?%.

NOVEL AND SPECIFIC INHIBITORS OF CYTOCHROME P450 26 RETINOIC ACID HYDROLASE

The present disclosure is generally directed to compositions and methods for treating diseases that are ameliorated by the inhibition of CYP26 mediated retinoic acid metabolism.