38512-77-5

Basic information

• Product Name: Benzoic acid, 2,3,4,5-tetrafluoro-6-methoxy-
• CAS NO: 38512-77-5
• Molecular Formula: C8H4F4O3
• Molecular Weight: 224.112
• Mol File: 38512-77-5.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 2,3,4,5-tetrafluoro-6-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 2,3,4,5-tetrafluoro-6-methoxy-(38512-77-5)
• EPA Substance Registry System: Benzoic acid, 2,3,4,5-tetrafluoro-6-methoxy-(38512-77-5)

Safety Data

• Hazardous Substances Data: 38512-77-5(Hazardous Substances Data)

Upstream product

• 4732-69-8 Chloro-oxo-acetic acid 
• 122-51-0 orthoformic acid triethyl ester 
• 602-94-8 Pentafluorobenzoic acid 
• 109-88-6 magnesium methanolate 
• 67-56-1 methanol 
• 2251-50-5 pentafluorobenzoylchloride 
• 79-37-8 oxalyl dichloride 
• 358352-95-1 2-Methoxy-3,4,5,6-tetrafluorobenzoyl chloride 

Downstream Products

• 358352-95-1 2-Methoxy-3,4,5,6-tetrafluorobenzoyl chloride 
• 15068-09-4 ethyl 2-hydroxy-3,4,5,6-tetrafluorobenzoate 
• 22105-26-6 2-acetyloxy-3,4,5,6-tetrafluorobenzoic acid 
• 321-95-9 1,2,3,4-tetrafluoro-5-methoxybenzene 
• 14742-36-0 2-hydroxy-3,4,5,6-tetrafluorobenzoic acid 
• 685829-70-3 Ethyl 2-(2-methoxy-3,4,5,6-tetrafluorobenzoyl)-3-oxobutanoate 
• 435273-77-1 ethyl 2-(2-methoxy-3,4,5,6-tetrafluorobenzoyl)-3-oxobutanoate 

Relevant articles and documents

A convenient and efficient approach to polyfluorosalicylic acids and their tuberculostatic activity

We have developed the practical method for polyfluorosalicylic acids synthesis via nucleophilic ortho-mono-substitution of fluorine atom with magnesium methoxide. We have managed to increase the yield of targeted polyfluorosalicylic acids from good to quantitative. We have studied the tuberculostatic activity of polyfluorosalicylic acids. It has been found that minimum inhibitory concentration (MIC) of compounds is from 0.7 to 6.5 μg/mL depending on the structure.

The selective ortho-methoxylation of pentafluorobenzoic acid - A new way to tetrafluorosalicylic acid and its derivatives

A simple and efficient preparation of tetrafluorosalicylic acid has been developed which involves a selective substitution of fluorine in pentafluorobenzoic acid with methoxyl group by magnesium methoxide. The synthesis of 2,6-dimethoxy-3,4,5-trifluorobenzoic acid, 4,5,6-trifluororesorcinol and its dimethoxy ether is described.

5-Amino and 5-hydroxy-6,8-difluoroquinolones as antibacterial agents

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