385442-12-6Relevant academic research and scientific papers
Iron catalyzed oxidative assembly of N-heteroaryl and aryl metal reagents using oxygen as an oxidant
Liu, Kun Ming,Liao, Lian Yan,Duan, Xin Fang
supporting information, p. 1124 - 1127 (2015/01/09)
An equivalent amount of N-heteroaryl and aryl Grignard or lithium reagents, after mediation by an equivalent of titanate, was facilely coupled to furnish N-heteroaryl-aryl compounds under the catalysis of FeCl3/TMEDA at ambient temperature using oxygen as an oxidant. Most of the common N-heteroaryls were all good candidates, and thus provided a general, green and pratical protocol for the flexible construction of various N-heteroaryl-aryl structures. This journal is
N -heterocyclic carbene-palladium(II)-1-methylimidazole complex-catalyzed direct C-H bond arylation of (Benz)imidazoles with aryl chlorides
Gu, Zheng-Song,Chen, Wen-Xin,Shao, Li-Xiong
, p. 5806 - 5811 (2014/07/08)
(Benz)imidazoles can be efficiently functionalized by (hetero)aryl chlorides via direct C-H bond arylation in the presence of a well-defined NHC-Pd(II)-Im complex. Under the optimal conditions, various activated, unactivated, and deactivated (hetero)aryl chlorides were successfully applied as the arylating reagents to achieve the 2-(hetero)aryl (benz)imidazoles in acceptable to high yields, giving a facile and alternative methodology for the direct C-H bond arylation of (benz)imidazoles.
Phosphines with 2-imidazolium and para-phenyl-2-imidazolium moieties - Synthesis and application in two-phase catalysis
Brauer, David J.,Kottsieper, Konstantin W.,Liek, Christian,Stelzer, Othmar,Waffenschmidt, Horst,Wasserscheid, Peter
, p. 177 - 184 (2007/10/03)
Deprotonation of 1-n-butyl-3-methyl-imidazolium chloride or hexafluorophosphate with n-butyl lithium and subsequent reaction of the intermediate 2,3-dihydro-imidazol-2-ylidene with diphenylchlorophosphine affords the 2-imidazolium phosphines 3a or 3b. The
