38554-27-7Relevant academic research and scientific papers
Mild synthesis method of diaryl substituted benzenesulfonyl hydrazine
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Paragraph 0035-0038, (2020/06/17)
A mild synthesis method of diaryl substituted benzenesulfonyl hydrazine comprises the following steps: 1, sequentially adding N'-sulfonyl aryl hydrazine, a catalyst and an alkali into a round bottom flask containing 5 mL of methanol in an air atmosphere, and stirring for 4-8 h at a room temperature; 2, monitoring a reaction by thin-layer chromatography; 3, after the monitoring of the reaction by the thin-layer chromatography is finished, adding 20 mL of saturated edible salt water into the reaction system, extracting for three times, and mixing obtained organic phases, and adding anhydrous sodium sulfate into the organic phase for drying, carrying out reduced pressure distillation to remove the solvent, and carrying out column chromatography separation to obtain the pure product. The product molecule polysubstituted hydrazine prepared by the method is an extremely common and important organic fragment and widely exists in natural products, drug molecules and material molecules, so thatthe obtained product has a considerable application prospect.
Visible-Light Photoredox-Catalyzed Aminosulfonylation of Diaryliodonium Salts with Sulfur Dioxide and Hydrazines
Liu, Nai-Wei,Liang, Shuai,Manolikakes, Georg
supporting information, p. 1308 - 1319 (2017/04/18)
A photoredox-catalyzed three-component synthesis of N-aminosulfonamides starting from diaryliodonium salts, hydrazines and sulfur dioxide is reported. This reaction proceeds under mild conditions at room temperature and is driven by visible light. A simple bisulfite salt can be used as a readily available and easy-to-handle sulfur dioxide source. Mechanistic studies support a catalytic photoredox pathway with the diaryliodonium salt as convenient source for aryl radicals. (Figure presented.).
A copper-catalyzed three-component reaction of triethoxysilanes, sulfur dioxide, and hydrazines
Wang, Xianbo,Xue, Lijun,Wang, Zhiyong
supporting information, p. 4056 - 4058 (2014/08/18)
A three-component reaction of triethoxysilanes, sulfur dioxide, and hydrazines catalyzed by copper(II) acetate is reported, leading to N-aminosulfonamides in good yields. Not only triethoxy(aryl)silanes but also triethoxy(alkyl)silanes are compatible during the process of insertion of sulfur dioxide. Additionally, diethoxydiarylsilanes are suitable under the conditions as well.
Aminosulfonylation of aromatic amines, sulfur dioxide and hydrazines
Zheng, Danqing,Li, Ying,An, Yuanyuan,Wu, Jie
supporting information, p. 8886 - 8888 (2014/08/05)
A facile route to aryl N-aminosulfonamides under mild conditions is provided. The reaction of aromatic amines (including heteroaromatic amines), sulfur dioxide, and hydrazines proceeds efficiently with good functional group tolerance. The in situ generated diazonium ion is involved in the aminosulfonylation process. This journal is the Partner Organisations 2014.
Metal-free aminosulfonylation of aryldiazonium tetrafluoroborates with DABCO×(SO2)2 and hydrazines
Zheng, Danqing,An, Yuanyuan,Li, Zhenhua,Wu, Jie
supporting information, p. 2451 - 2454 (2014/03/21)
The coupling of aryldiazonium tetrafluoroborates, DABCO×(SO 2)2, and hydrazines under metal-free conditions leads to the formation of aryl N-aminosulfonamides. The reaction proceeds smoothly at room temperature and shows broad functional-group tolerance. A radical process is proposed for this transformation. The coupling of aryldiazonium tetrafluoroborates, DABCO×(SO2)2, and hydrazines under metal-free conditions leads to the formation of aryl N-aminosulfonamides. The reaction proceeds under mild reaction conditions, is fast, has a broad substrate scope, and gives the products in high yiels (21 examples). A plausible mechanism that involves a radical process is also proposed. Copyright
