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N-phenylbenzenesulfonohydrazide is an organic compound with the chemical formula C12H12N2O2S. It is a white crystalline solid that is soluble in water and various organic solvents. N-phenylbenzenesulfonohydrazide is primarily used as a reagent in chemical analysis, particularly for the detection and determination of aldehydes and ketones. It reacts with these carbonyl compounds to form a colored hydrazone derivative, which can be analyzed spectrophotometrically. N-phenylbenzenesulfonohydrazide is also known for its potential applications in the synthesis of pharmaceuticals and other organic compounds. Due to its reactivity and utility, it is an important tool in the field of analytical chemistry and organic synthesis.

6596-69-6

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6596-69-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 6596-69-6 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 6,5,9 and 6 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 6596-69:
(6*6)+(5*5)+(4*9)+(3*6)+(2*6)+(1*9)=136
136 % 10 = 6
So 6596-69-6 is a valid CAS Registry Number.

6596-69-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name N-phenylsulfonyl-4-nitroaniline

1.2 Other means of identification

Product number -
Other names Benzenesulfonic acid, 2-phenylhydrazide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:6596-69-6 SDS

6596-69-6Relevant academic research and scientific papers

HYDRAZIDE DERIVATIVES AND THEIR SPECIFIC USE AS ANTIBACTERIAL AGENTS BY CONTROLLING ACINETOBACTER BAUMANNII BACTERIUM

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Page/Page column 48-49, (2020/09/08)

The present invention relates to compounds of the following general formula (I): or a pharmaceutically acceptable salt and/or solvate thereof, their use as a drug, in particular as antibacterial agent, notablyforpreventingand/or treating disorders associa

The triple role of rongalite in aminosulfonylation of aryldiazonium tetrafluoroborates: synthesis of N-aminosulfonamides via a radical coupling reaction

Wang, Miao,Tang, Bo-Cheng,Wang, Jun-Gang,Xiang, Jia-Chen,Guan, Ao-Yu,Huang, Ping-Ping,Guo, Wu-Yinzheng,Wu, Yan-Dong,Wu, An-Xin

supporting information, p. 7641 - 7644 (2018/07/15)

A simple and convenient method for N-aminosulfonamide synthesis from the cross-coupling of aryldiazonium tetrafluoroborates and rongalite under metal-free, oxidant-free, and room-temperature conditions is reported. This method does not require an external amine source, with the aryldiazonium tetrafluoroborates participating as both an aryl radical and a potential amine source in the transformation. Mechanistic studies revealed that rongalite could act as a radical initiator, a sulfur dioxide surrogate and a reducing reagent simultaneously in this reaction.

N-PHENYL-N'-PHENOXYCARBONYL-PHENYLSULFONHYDRAZIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME

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Paragraph 0040; 0041; 0044; 0045, (2018/02/04)

The present invention relates to a N-phenyl-N'-phenoxycarbonyl-phenylsulfonhydrazide derivative with excellent inhibitory activity on PGE2 production, a method for preparing the same and a pharmaceutical composition comprising the same as an ac

Visible-Light Photoredox-Catalyzed Aminosulfonylation of Diaryliodonium Salts with Sulfur Dioxide and Hydrazines

Liu, Nai-Wei,Liang, Shuai,Manolikakes, Georg

supporting information, p. 1308 - 1319 (2017/04/18)

A photoredox-catalyzed three-component synthesis of N-aminosulfonamides starting from diaryliodonium salts, hydrazines and sulfur dioxide is reported. This reaction proceeds under mild conditions at room temperature and is driven by visible light. A simple bisulfite salt can be used as a readily available and easy-to-handle sulfur dioxide source. Mechanistic studies support a catalytic photoredox pathway with the diaryliodonium salt as convenient source for aryl radicals. (Figure presented.).

Hit-to-lead optimization of phenylsulfonyl hydrazides for a potent suppressor of PGE2 production: Synthesis, biological activity, and molecular docking study

Kim, Minju,Lee, Sunhoe,Park, Eun Beul,Kim, Kwang Jong,Lee, Hwi Ho,Shin, Ji-Sun,Fischer, Katrin,Koeberle, Andreas,Werz, Oliver,Lee, Kyung-Tae,Lee, Jae Yeol

, p. 94 - 99 (2015/12/18)

Preliminary hit-to-lead optimization of a novel series of phenylsulfonyl hydrazide derivatives, which were derived from the high throughput screening hit compound 1 (IC50 = 5700 nM against PGE2 production), for a potent suppressor of

An efficient synthesis of sulfonylhydrazides and sulfonylsemicarbazides by utilizing alumina as a catalyst

Safaei-Ghomi, Javad

, p. 1561 - 1563 (2008/09/16)

Sulfonyl hydrazides and sulfonyl semicarbazides are readily prepared by the reacting of hydrazine derivatives with sulfonyl chlorides in the presence of basic alumina under solvent-free conditions. Reaction of a sulfonyl chloride with t-butylcarbazate, followed by hydrolysis provides the corresponding sulfonyl hydrazides in higher yield and shorter time than previously reported.

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