386-16-3Relevant academic research and scientific papers
A simple copper-catalyzed synthesis of tertiary acyclic amides
Racine, Emilie,Monnier, Florian,Vors, Jean-Pierre,Taillefer, Marc
supporting information; experimental part, p. 2818 - 2821 (2011/07/09)
The N-arylation of aromatic and aliphatic secondary acyclic amides, known to be poor nucleophiles, has been accomplished using a simple and cheap copper catalytic system. The corresponding tertiary acyclic amides, which can be found in numerous biologically active compounds, have been obtained in good to excellent yields.
