386230-13-3Relevant academic research and scientific papers
Mechanistic considerations pertaining to the solvolysis of paclitaxel analogs bearing ester groups at the C2′ position
Klis, Wieslaw A.,Sarver, Jeffrey G.,Erhardt, Paul W.
, p. 7747 - 7750 (2001)
Dilute solutions of paclitaxel-related derivatives having chloroacetyl esters in the C2′ position undergo ready methanolysis according to pseudo first-order kinetics while more concentrated solutions appear to be stabilized, possibly by the formation of h
Design and synthesis of a combinatorial chemistry library of 7-acyl, 10-acyl, and 7,10-diacyl analogues of paclitaxel (taxol) using solid phase synthesis
Jagtap, Prakash G.,Baloglu, Erkan,Barron, Donna M.,Bane, Susan,Kingston, David G. I.
, p. 1136 - 1142 (2007/10/03)
A series of 10-acyl and 7,10-diacyl paclitaxel analogues (7a-7e and 9a-9u) have been synthesized using a solid phase combinatorial chemistry approach, and a second series of 7-acyl-10-deacetylpaclitaxel analogues have been prepared by conventional chemist
