386743-16-4

Upstream product

• 24164-73-6 methyl (S)-2-(benzyloxycarbonyl-methyl-amino)-3-phenylpropionate 
• 17191-53-6 Cbz-(NMe)Phe-NH₂ 
• 1329627-28-2 (S)-N,2-dimethyl-N-((S)-2-phenyl-1-(thiazol-2-yl)ethyl)propane-2-sulfinamide 
• 1329627-20-4 (S)-2-methyl-N-((S)-2-phenyl-1-(thiazol-2-yl)ethyl)propane-2-sulfinamide 
• 386743-17-5 Methyl-((S)-2-phenyl-1-thiocarbamoyl-ethyl)-carbamic acid benzyl ester 
• 2899-07-2 (S)-N-benzyloxycarbonyl-N-methyl-phenyl alanine 
• 386743-18-6 (S)-N-Cbz-N-methyldolaphenine 

Relevant academic research and scientific papers

Efficient total synthesis of dysidenin, dysidin, and barbamide

The total syntheses of three trichloroleucine-derived marine natural products-dysidenin, dysidin, and barbamide-capitalized on a practical and highly diastereoselective ruthenium catalyzed radical chloroalkylation of N-acyloxazolidinones as the key step. Copyright

Synthesis of the marine natural product barbamide

The first total synthesis of the trichlorinated natural product barbamide is described. The convergent approach involves coupling (S)-3-trichloromethylbutanoyl chloride with Meldrum's acid (2,2-dimethyl-1,3-dioxane-4,6-dione) to give 15 followed by additi