3868-03-9

Usage

Uses

Used in Pharmaceutical and Chemical Synthesis:
1,6:2,3-Dianhydro-β-D-mannopyranose is used as a starting material for the synthesis of complex carbohydrates and glycosides, due to its unique cyclic structure and anhydro bridges, which facilitate the formation of diverse carbohydrate derivatives.
Used in Drug Delivery Systems:
1,6:2,3-Dianhydro-β-D-mannopyranose is utilized as a component in drug delivery systems, leveraging its structural properties to enhance the delivery and targeting of therapeutic agents, potentially improving their efficacy and bioavailability.
Used in Bioactive Compound Synthesis:
1,6:2,3-Dianhydro-β-D-mannopyranose is employed as a building block in the synthesis of novel bioactive compounds, given its potential to contribute to the development of new pharmaceutical agents with unique modes of action.
Used in Anti-inflammatory and Anti-cancer Research:
1,6:2,3-Dianhydro-β-D-mannopyranose is studied for its potential anti-inflammatory and anti-cancer properties, making it a promising candidate for further research into its therapeutic applications in treating inflammatory conditions and cancer.
Used in Research and Development:
1,6:2,3-Dianhydro-β-D-mannopyranose is an interesting molecule for research and development in the fields of chemistry and medicine, given its unique structural features and potential applications in various industries.

Upstream product

• 139437-39-1 1,6-anhydro-2-deoxy-2-iodo-β-D-glucopyranose 
• 9004-34-6 cellulose 
• 824-94-2 p-methoxybenzyl chloride 

Downstream Products

• 127529-87-7 1,6:2,3-dianhydro-4-O-(6-O-acetyl-2,3,4-tri-O-benzyl-β-D-galactopyranosyl)-β-D-mannopyranose 
• 86861-51-0 4-O-(6-O-Acetyl-2,3,4-tri-O-benzyl-β-D-mannopyranosyl)-1,6:2,3-dianhydro-β-D-mannopyranose 
• 107952-50-1 1,6:2,3-dianhydro-4-O-(2,3,5,6-tetra-O-benzyl-β-D-glucopyranosyl)-β-D-mannopyranose 
• 107952-48-7 1,6:2,3-dianhydro-4-O-(2,3,5,6-tetra-O-benzyl-α-D-glucopyranosyl)-β-D-mannopyranose 
• 213594-43-5 1,6:3,4-dianhydro-2-O-benzyl-β-D-altropyranose 
• 33208-47-8 4-O-benzyl-1,6:2,3-dianhydro-β-D-mannopyranose 
• 91510-63-3 4-O-Allyl-1,6:2,3-dianhydro-β-D-mannopyranose 
• 3868-08-4 1,6:2,3-dianhydro-4-O-(4-toluenesulfonyl)-β-D-mannopyranose 
• 55682-47-8 1,6-anhydro-2-azido-4-O-benzyl-2-deoxy-β-D-glucopyranose 
• 105265-70-1 (1R,2S,3R,4R,5R)-2-Allyloxy-4-azido-3-benzyloxy-6,8-dioxa-bicyclo[3.2.1]octane 
• 949524-11-2 1,6-anhydro-3-deoxy-3-iodo-β-D-altropyranose 
• 3868-04-0 1,6:3,4-dianhydro-β-D-altropyranose 
• 417711-01-4 1,6-anhydro-2-O-benzoyl-3-deoxy-3-fluoro-β-D-mannopyranose 
• 88142-85-2 1,6-Anhydro-3-deoxy-3-fluoro-β-D-mannopyranose 

Relevant academic research and scientific papers

High-pressure fast-pyrolysis, fast-hydropyrolysis and catalytic hydrodeoxygenation of cellulose: Production of liquid fuel from biomass

A lab-scale, high-pressure, continuous-flow fast-hydropyrolysis and vapor-phase catalytic hydrodeoxygenation (HDO) reactor has been successfully designed, built and tested with cellulose as a model biomass feedstock. We investigated the effects of pyrolysis temperature on high-pressure cellulose fast-pyrolysis, hydrogen on high-pressure cellulose fast-hydropyrolysis, reaction pressure (27 bar and 54 bar) on our reactor performance and candidate catalysts for downstream catalytic HDO of cellulose fast-hydropyrolysis vapors. In this work, a liquid chromatography-mass spectrometry (LC-MS) method has been developed and utilized for quantitative characterization of the liquid products. The major compounds in the liquid from cellulose fast-pyrolysis (27 bar, 520 °C) are levoglucosan and its isomers, formic acid, glycolaldehyde, and water, constituting 51 wt%, 11 wt%, 8 wt% and 24 wt% of liquid respectively. Our results show that high pressures of hydrogen do not have a significant effect on the fast-hydropyrolysis of cellulose at 480 °C but suppress the formation of reactive light oxygenate species like glycolaldehyde and formic acid at 580 °C. The formation of permanent gases (CO, CO2, CH4) and glycolaldehyde and formic acid increased with increasing pyrolysis temperature in the range of 480 °C-580 °C in high-pressure cellulose fast-pyrolysis, in the absence of hydrogen. Candidate HDO catalysts Al 2O3, 2% Ru/Al2O3 and 2% Pt/Al 2O3 resulted in extents of deoxygenation of 20%, 22% and 27%, respectively, but led to carbon loss to gas phase as CO and CH4. These catalysts provide useful insights for other candidate HDO catalysts for improving the extent of deoxygenation with higher carbon recovery in the liquid product.

AN EFFICIENT AND SCALABLE PROCESS FOR THE MANUFACTURE OF FONDAPARINUX SODIUM

The present invention relates to a process for the synthesis of the Factor Xa anticoagulent Fondaparinux and related compounds. The invention relates, in addition, to efficient and scalable processes for the synthesis of various intermediates useful in the synthesis of Fondaparinux and related compounds.

An Expeditious and Stereocontrolled Preparation of 2-Azido-2-deoxy-β-D-glucopyranose Derivatives from D-Glucal

1,6-Anhydro-2-azido-2-deoxy-β-D-glucopyranose has been prepared by a two-step procedure from D-glucal and transformed into precursors useful in the synthesis of oligosaccharides.