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2-(3,4-dihydroxyphenyl)-2-[(methyl)oxy]-1-(isopropylamino)ethane hydrochloride, also known as Metoprolol hydrochloride, is a pharmaceutical compound used as a selective beta-1 adrenergic receptor blocker. It is primarily employed in the treatment of conditions such as hypertension, angina, and certain types of arrhythmias. Metoprolol works by reducing the heart's workload and slowing its rate, which in turn helps to lower blood pressure and alleviate chest pain. The hydrochloride salt form of the drug enhances its solubility and absorption when administered orally. As a medication, Metoprolol is widely recognized for its effectiveness in managing cardiovascular issues, and it is an essential component in the treatment regimen for many patients with heart-related conditions.

3868-81-3

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3868-81-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 3868-81-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,8,6 and 8 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 3868-81:
(6*3)+(5*8)+(4*6)+(3*8)+(2*8)+(1*1)=123
123 % 10 = 3
So 3868-81-3 is a valid CAS Registry Number.

3868-81-3Downstream Products

3868-81-3Relevant academic research and scientific papers

Study of interaction between agonists and Asn293 in helix VI of human β2-adrenergic receptor

Zuurmond, Helene M.,Hessling, Jutta,Blueml, Klaus,Lohse, Martin,Ijzerman, Adriaan P.

, p. 909 - 916 (1999)

Previously, we demonstrated the involvement of Asn293 in helix VI of the human β2-adrenergic receptor in stereoselective agonist recognition and activation. In the present study, we have further explored the role of this residue by synthesizing

MECHANISM OF THE ETHERIFICATION OF 2-ALKYLAMINO-1-PHENYLETHANOL DERIVATIVES

Venter, D. P.,Greeff, D. F.

, p. 305 - 307 (2007/10/02)

Derivatives of 2-alkylamino-1-(4-hydroxyphenyl)-1-ethanol have been converted to the β-methylethers in good yield.Etherification of 2-alkylamino-1-(4-methoxyphenyl)-1-ethanol could not be accomplished.Based on this unreactivity, a mechanism is proposed wh

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