3871-28-1

Basic information

• Product Name: ETHYL N-METHOXYCARBAMATE
• Synonyms: ETHYL N-METHOXYCARBAMATE;ethyl methoxycarbamate
• CAS NO: 3871-28-1
• Molecular Formula: C₄H₉NO₃
• Molecular Weight: 119.12
• Mol File: 3871-28-1.mol

Chemical Properties

• Boiling Point: 50°/0.5mm
• Flash Point: °C
• Appearance: /
• Density: 1.052g/cm³
• Refractive Index: 1.404
• CAS DataBase Reference: ETHYL N-METHOXYCARBAMATE(CAS DataBase Reference)
• NIST Chemistry Reference: ETHYL N-METHOXYCARBAMATE(3871-28-1)
• EPA Substance Registry System: ETHYL N-METHOXYCARBAMATE(3871-28-1)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 3871-28-1(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
ETHYL N-METHOXYCARBAMATE is used as a reagent in organic synthesis for the preparation of certain pharmaceuticals and agricultural chemicals. Its versatility in chemical reactions makes it a valuable component in the synthesis of various compounds.
Used in Pesticide Industry:
ETHYL N-METHOXYCARBAMATE is used as a pesticide and a carbamate insecticide in the agricultural sector. It helps control pests and insects that can damage crops, thereby contributing to increased agricultural productivity.

InChI:InChI=1/C4H9NO3/c1-3-8-4(6)5-7-2/h3H2,1-2H3,(H,5,6)

Upstream product

• 149-73-5 trimethyl orthoformate 
• 745829-70-3 ethyl N-chloro-N-methoxycarbamate 
• 67-56-1 methanol 
• 745829-72-5 ethyl N-acetoxy-N-methoxycarbamate 
• 589-41-3 ethyl N-hydroxylcarbamate 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 67-62-9 O-Methylhydroxylamin 
• 474510-43-5 (N-methoxy-N-methoxyethyl)carbamic acid ethyl ester 

Relevant articles and documents

Geminal systems: 64. N-alkoxy-N-chloroureas and N,N-dialkoxyureas

Molecular and crystal structures of N-alkoxy-N-chloroureas and N,N-dialkoxyureas were studied together with those of N-alkoxyureas as reference compounds. N-Alkoxy-N-chloroureas were found to have an elongated N - Cl bond and a shortened N-O(Alk) bond due to the nO(Alk)→σN-Cl anomeric effect. Alcoholysis of N-alkoxy-N-chloro derivatives of urea, N′-arylureas, and carbamates in the presence of silver trifluoroacetate leads to sterically hindered N,N-dialkoxyureas, N,N-dialkoxy-N′-arylureas, and N,N-dialkoxycarbamates, respectively.

Geminal systems 50. Synthesis and alcoholysis of N-acyloxy-N-alkoxy derivatives of ureas, carbamates, and benzamides

Procedures were developed for the synthesis of N-acyloxy-N-alkoxy derivatives of ureas, carbamates, and benzamides by the reactions of the corresponding N-alkoxy-N-chloro derivatives with sodium carboxylates in MeCN. N-Chloro-N-ethoxy-p-toluenesulfonamide was inert in this reaction. Alcoholysis of N-acyloxy-N-alkoxy derivatives of ureas, carbamates, and tert-alkylamines afforded the corresponding N,N-dialkoxy derivatives, whereas alcoholysis of N-acetoxy-N-ethoxybenzamide gave rise to alkyl benzoates.