387353-94-8

Basic information

• Product Name: 5-(fluoro-dimethylsilanyl)-3-methyl-1-phenyl-1H-pyrazole
• Synonyms: 5-(fluoro-dimethylsilanyl)-3-methyl-1-phenyl-1H-pyrazole
• CAS NO: 387353-94-8
• Molecular Weight: 234.348
• Mol File: 387353-94-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(fluoro-dimethylsilanyl)-3-methyl-1-phenyl-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(fluoro-dimethylsilanyl)-3-methyl-1-phenyl-1H-pyrazole(387353-94-8)
• EPA Substance Registry System: 5-(fluoro-dimethylsilanyl)-3-methyl-1-phenyl-1H-pyrazole(387353-94-8)

Safety Data

• Hazardous Substances Data: 387353-94-8(Hazardous Substances Data)

Upstream product

• 1128-54-7 3-methyl-1-phenyl-1H-pyrazole 
• 387354-06-5 3-methyl-5-(dimethylphenylsilyl)-1-phenylpyrazole 

Downstream Products

• 89-25-8 edaravone 

Relevant articles and documents

Synthesis and reactions of silylated and stannylated 1,2-azoles

Silicon or tin 4-metalated pyrazoles and isoxazoles are synthesized by silyl- or stannylcupration from 4-haloazoles. On the other hand, 5-metalated pyrazoles are prepared by reaction of 5-un-substituted pyrazoles with LDA and subsequent treatment with chlorosilanes and chlorostannanes. Furthermore, starting from 5-unsubstituted 4-halopyrazoles and applying both methodologies, 4,5-dimetalated pyrazoles bearing silyl groups different from trimethylsilyl or tributylstannyl groups are obtained. Some regioselective ipso-substitutions are also studied.