38782-65-9

Basic information

• Product Name: 2,2'-Methylenebis(phenol)diacetate
• Synonyms: 2,2'-Methylenebis(phenol)diacetate
• CAS NO: 38782-65-9
• Molecular Formula: C₁₇H₁₆O₄
• Molecular Weight: 284.31
• Mol File: 38782-65-9.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2,2'-Methylenebis(phenol)diacetate(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2'-Methylenebis(phenol)diacetate(38782-65-9)
• EPA Substance Registry System: 2,2'-Methylenebis(phenol)diacetate(38782-65-9)

Safety Data

• Hazardous Substances Data: 38782-65-9(Hazardous Substances Data)

Upstream product

• 2467-02-9 Bis(2-hydroxyphenyl)methane 
• 108-95-2 phenol 
• 108-24-7 acetic anhydride 
• 835-11-0 2,2'-dihydroxybenzophenone 

Downstream Products

• 60312-53-0 3,3'-diacetyl-2,2'-dihydroxydiphenylmethane 
• 83143-08-2 1-[3-(3-Acetyl-2-hydroxy-benzoyl)-2-hydroxy-phenyl]-ethanone 
• 33427-60-0 2,2'-Dihydroxy-5,5'-diacetylbenzophenon 

Relevant articles and documents

Development of chemical probes: Toward the mode of action of a methylene-linked di(aryl acetate) E1

Analogues of the novel inhibitor of the PI3-K/PKB pathway, 2-[5-(2-chloroethyl)-2-acetoxy-benzyl]-4-(2-chloroethyl)-phenyl acetate (E1), have been prepared and preliminary SAR performed. This established that at least one of the chloroethyl para-substituents could be removed or modified and the ability to inhibit PKB/Akt activation retained. Synthetic methodologies were then developed to methylene-linked aryl acetates for use as molecular probes to identify the target of compound E1.