38806-26-7

Usage

Uses

Used in Pharmaceutical Industry:
N-Methyl-N-ethylacetamide is utilized as a solvent in various chemical reactions, particularly in the pharmaceutical sector. Its properties make it suitable for facilitating reactions that are crucial for the synthesis of pharmaceutical compounds.
Used in Organic Compound Production:
Beyond its solvent role, N-Methyl-N-ethylacetamide also serves as a reactant in the production of other organic compounds. Its reactivity and stability contribute to the formation of desired products in organic synthesis processes.

Upstream product

• 515-46-8 Ethyl benzenesulfonate 
• 7449-74-3 N-methyl-N-trimethylsilylacetamide 
• 598-56-1 N,N-dimethyl-ethanamine 
• 201230-82-2 carbon monoxide 
• 121-44-8 triethylamine 

Downstream Products

• 624-78-2 N-Ethylmethylamine 
• 71-50-1 acetate 

Relevant academic research and scientific papers

N-Alkylation of N-trimethylsilyl derivatives of lactams, amides, and imides with alkyl sulfonates

The reaction of N-trimethylsilyl derivatives of amides and imides with alkyl sulfonates on heating affords the corresponding N-alkyl derivatives and trimethylsilyl sulfonates.

PROCESS FOR PREPARING SECONDARY AMIDES BY CARBONYLATION OF A CORRESPONDING TERTIARY AMINE

The present invention relates to a process for preparing secondary amides with good selectivity by carbonylating a corresponding tertiary amine with carbon monoxide in a reaction mixture in the presence of a metal catalyst and in the presence of a halogen containing promoter. The metal catalyst comprises palladium. A same or even a much better catalytic activity can be obtained with palladium than with the much more expensive rhodium, especially when the palladium is used in a low concentration. Moreover, also a good selectivity can be achieved.