N-Methyl-N-ethylacetamide

Base Information

• Chemical Name: N-Methyl-N-ethylacetamide
• CAS No.: 38806-26-7
• Molecular Formula: C5H11 N O
• Molecular Weight: 101.148
• Hs Code.: 2924199090
• Mol file: 38806-26-7.mol

Synonyms:N-Ethyl-N-methylacetamide;N-Methyl-N-ethylacetamide

Chemical Property of N-Methyl-N-ethylacetamide

Chemical Property:

• Boiling Point: 170.7±8.0 °C(Predicted)
• PKA: -0.41±0.70(Predicted)
• PSA: 20.31000
• Density: 0.876±0.06 g/cm3(Predicted)
• LogP: 0.48460
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98% ^*data from raw suppliers

N-ethyl-N-methylacetamide 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-Methyl-N-ethylacetamide

There total 3 articles about N-Methyl-N-ethylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

Ethyl benzenesulfonate (515-46-8) + N-methyl-N-trimethylsilylacetamide (7449-74-3) → N-ethyl-N-methylacetamide (38806-26-7) + trimethylsilyl benzenesulfonate (17882-06-3)

Guidance literature:

Heating;

DOI:10.1007/s11172-020-2775-x

Reference yield:

N,N-dimethyl-ethanamine (598-56-1) + carbon monoxide (201230-82-2) → diethylacetamide (685-91-6) + N-ethyl-N-methylacetamide (38806-26-7)

Guidance literature:

With tertamethylammonium iodide; palladium dichloride; In 1-methyl-pyrrolidin-2-one; at 20 - 240 ℃; for 1.28333h; under 7500.75 - 48754.9 Torr; Autoclave;

Reference yield:

carbon monoxide (201230-82-2) + triethylamine (121-44-8) → diethylacetamide (685-91-6) + N-ethyl-N-methylacetamide (38806-26-7) + N,N-diethylpropanamide (1114-51-8)

Guidance literature:

With tertamethylammonium iodide; palladium dichloride; In 1-methyl-pyrrolidin-2-one; at 20 - 240 ℃; for 2.33333h; under 7500.75 - 48754.9 Torr; Autoclave;

upstream raw materials:

carbon monoxide

triethylamine

N,N-dimethyl-ethanamine

Ethyl benzenesulfonate

Downstream raw materials:

N-Ethylmethylamine

acetate

Refernces

• 1、 -. "PROCESS FOR PREPARING SECONDARY AMIDES BY CARBONYLATION OF A CORRESPONDING TERTIARY AMINE". Page/Page column 4. . Retrieved 2010/06/14.