3883-14-5

Usage

Uses

1. Used in Chemical Research:
Benzene, 1-chloro-4-(2,2,2-trichloroethyl)is used as a compound in chemical research to study the effects of singlet vs triplet reactivity of photogenerated α,n-didehydrotoluenes. This application is crucial for understanding the underlying mechanisms and reactions involving these types of molecules, which can be beneficial for the development of new chemical processes and products.
2. Used in Polar Effect Studies:
In addition to its use in studying singlet vs triplet reactivity, Benzene, 1-chloro-4-(2,2,2-trichloroethyl)is also utilized in research focusing on the polar effect in reactions with substituted benzyl radicals and carbon tetrachloride. This application helps scientists gain insights into the influence of polar effects on the reactivity and behavior of these molecules, which can be valuable for designing and optimizing chemical reactions and processes in various industries.

Upstream product

• 75-35-4 1,1-Dichloroethylene 
• 106-47-8 4-chloro-aniline 
• 75-62-7 Bromotrichloromethane 
• 56669-78-4 para-chlorobenzylbis(dimethylglyoximato)(pyridine)cobalt(III) 
• 56-23-5 tetrachloromethane 
• 17876-99-2 (4-chlorobenzyl)trimethylsilane 
• 2028-74-2 p-chlorobenzenediazonium chloride 

Downstream Products

• 1878-66-6 4-chlorophenylacetic Acid 

Relevant academic research and scientific papers

A phenylacetic acid compound preparation method (by machine translation)

The invention relates to the field of chemical synthesis, in particular relates to a preparation method of the compound of phenylacetic acid. The present invention provides a preparation method of the compound of phenylacetic acid, the acid compounds of the structural formula states the benzene second grade shown in formula I, the preparation method comprises the following steps: (1) diazo addition reaction: formula II compound containing vinylidene chloride, acid, diazotization reagent, phase transfer catalyst and a copper catalyst in the system of the formula III compound: (2) hydrolysis reaction: the compound of formula III in the presence of acid hydrolysis of formula I compounds. The present invention provides a preparation method of and is simple, easy operation, low cost of raw materials, mild reaction conditions, low risk, does not need to use expensive noble metal catalyst and complex industrial operation means, the product quality is stable, therefore easy achievement of large-scale industrial production. (by machine translation)

Singlet vs Triplet Reactivity of Photogenerated α,n-Didehydrotoluenes

The reactivity of α,n-didehydrotoluenes (DHTs) in protic media (organic/aqueous mixtures) was explored by means of a combined computational and experimental approach. These intermediates were generated via a photoinduced double elimination process occurring in (chlorobenzyl)trimethylsilanes and led to the formation of a varied products distribution, depending on the isomer tested. Irradiation of ortho- and para-derivatives resulted, respectively, in the formation of triplet α,2- and α,4-DHTs, whose diradical reactivity led to both radical and polar products. On the other hand, irradiation of the meta-precursor led to the singlet α,3-DHT isomer. The latter showed a marked preference for the formation of polar products and this was rationalized, as supported by computational evidence, via the involvement of a zwitterionic species arising through interaction of the nucleophilic solvent with the benzylic position of the DHT.

HOMOLYTIC DISPLACEMENT AT CARBON VI. SYNTHESIS OF TRICHLOROETHYLARENES FROM BENZYLCOBALOXIMES

Benzylbis(dimethylglyoximato)pyridinecobalt(III) reacts with bromotrichloromethane at from 50 to 90 deg C in chloroform to give good yields of trichloroethylbenzene, which are higher when imidazole is present in the reaction mixture.Methyl- and polymethyl-substituted benzylbis(dimethylglyximato)pyridinecobalt(III) complexes give higher yields of the corresponding trichloroethylarenes (85-90percent), whereas 4-chlorobenzylbis(dimethylglyoximato)pyridinecobalt(III) only gives the 4-nitro-trichloroethylarene when imidazole is present during the reaciton.Similar reactions were observed with benzylcobaloximes and trichloromethanesulphonyl chloride both thermally and under irradiation by tungsten lamps through all-pyrex apparatus.The reactions are interpreted as a direct attack of the trichloromethyl radical on the α-carbon of the benzyl ligand.