3883-39-4

Usage

Uses

Used in Pharmaceutical Industry:
5-METHYL-2-VINYLPYRIDINE is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique chemical structure allows for the development of new drugs with potential therapeutic applications.
Used in Agrochemical Industry:
5-METHYL-2-VINYLPYRIDINE serves as a building block in the production of agrochemicals, such as pesticides and herbicides. Its incorporation into these products can enhance their effectiveness in controlling pests and weeds, thereby improving crop yields and protecting agricultural resources.
Used in Chemical Research:
As a member of the pyridine family, 5-METHYL-2-VINYLPYRIDINE is utilized in chemical research for the exploration of new reactions and the development of novel synthetic pathways. Its unique properties make it a valuable tool for understanding and advancing the field of organic chemistry.
Used in Material Science:
5-METHYL-2-VINYLPYRIDINE can be incorporated into the development of new materials with specific properties, such as polymers with tailored characteristics for use in various industries, including electronics, automotive, and aerospace.
Used in Environmental Applications:
Due to its reactivity, 5-METHYL-2-VINYLPYRIDINE can be employed in environmental remediation processes, such as the degradation of pollutants or the removal of harmful substances from water and soil. Its chemical properties make it a potential candidate for addressing environmental challenges.

Upstream product

• 3510-66-5 2-Bromo-5-methylpyridine 
• 92988-08-4 trivinylboroxin 
• 4985-92-6 5-methylpicolinaldehyde 
• 2065-66-9 methyl-triphenylphosphonium iodide 
• 7486-35-3 tri-n-butyl(vinyl)tin 

Downstream Products

• 1257521-42-8 2-(1-benzyl-pyrrolidin-3-yl)-5-methyl-pyridine 
• 1527527-91-8 N-(2-(5-methylpyridin-2-yl)ethyl)benzenesulfonamide 
• 132554-28-0 3-(5-Methyl-pyridin-2-yl)-1-phenyl-propan-1-one 
• 132554-32-6 1,5-Dimethyl-2-(2-benzoylethyl)pyridinium iodide 
• 136401-80-4 2-Imino-5-{4-[2-(5-methyl-pyridin-2-yl)-ethylsulfanyl]-benzyl}-thiazolidin-4-one 
• 136401-59-7 5-{4-[2-(5-Methyl-pyridin-2-yl)-ethylsulfanyl]-benzyl}-thiazolidine-2,4-dione 
• 136401-90-6 4-[2-(5-Methyl-pyridin-2-yl)-ethylsulfanyl]-phenylamine 

Relevant academic research and scientific papers

N2Phos - an easily made, highly effective ligand designed for ppm level Pd-catalyzed Suzuki-Miyaura cross couplings in water

A new biaryl phosphine-containing ligand from an active palladium catalyst for ppm level Suzuki-Miyaura couplings, enabled by an aqueous micellar reaction medium. A wide array of functionalized substrates including aryl/heteroaryl bromides are amenable, as are, notably, chlorides. The catalytic system is both general and highly effective at low palladium loadings (1000-2500 ppm or 0.10-0.25 mol%). Density functional theory calculations suggest that greater steric congestion in N2Phos induces increased steric crowding around the Pd center, helping to destabilize the 2?:?1 ligand-Pd(0) complex more for N2Phos than for EvanPhos (and less bulky ligands), and thereby favoring formation of the 1?:?1 ligand-Pdocomplex that is more reactive in oxidative addition to aryl chlorides.

PYRIMIDINE PDE10 INHIBITORS

The present invention is directed to pyrimidine compounds which are useful as therapeutic agents for the treatment of central nervous system disorders associated with phosphodiesterase 10 (PDE10). The present invention also relates to the use of such compounds for treating neurological and psychiatric disorders, such as schizophrenia, psychosis or Huntington's disease, and those associated with striatal hypofunction or basal ganglia dysfunction.

Cobalt-catalyzed addition of styrylboronic acids to 2-vinylpyridine derivatives

Treatment of 2-vinyl nitrogen-containing heteroaromatic compounds with styrylboronic acid in the presence of a cobalt catalyst and a base results in an addition reaction to afford the corresponding 4-phenyl-3-butenyl heteroarenes. The adjacent nitrogen atom is essential for the promotion of the reaction because the nitrogen accelerates the addition of the styryl cobalt species, generated by transmetalation, onto the vinyl group. The reaction represents a rare example of cobalt catalysis in the reactions of organoboronic acids. Accelerated addition: Treatment of 2-vinylpyridine derivatives with styrylboronic acids under cobalt catalysis results in addition reactions. This represents a rare example of the cobalt-catalyzed reaction of organoboronic acids. Cobalt shows catalytic activity similar to rhodium, and catalyzes an unprecedented assembly of organoboronic acids and activated alkenes. Copyright

2-CARBOXAMIDE-7-PIPERAZINYL-BENZOFURAN DERIVATIVES 774

The present invention relates to compounds of formula (I), wherein R1 is heteroaryl or heterocyclyl, optionally substituted;R2 is C1-4alkyl, heterocyclyl, C1-4alkylaryl, C1-4alkylheteroaryl, carbocycl

CARBAMATE AND UREA INHIBITORS OF 11BETA-HYDROXYSTEROID DEHYDROGENASE 1

This invention relates to novel compounds of the invention pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful for the therapeutic treatment of diseases associated with the modulation or inhibition of 11β-HSD1 in mammals. The invention further relates to pharmaceutical compositions of the novel compounds and methods for their use in the reduction or control of the production of cortisol in a cell or the inhibition of the conversion of cortisone to cortisol in a cell.

Ring-closing metathesis reactions on azinium salts: Straightforward access to quinolizinium cations and their dihydro derivatives

(Chemical Equation Presented) The ring-closing metathesis reaction of 1-butenyl-2-vinylpyridinium salts and 2-butenyl-1-vinylpyridinium salts using Grubbs second generation and Hoveyda-Grubbs catalysts proved to be an efficient approach to 3,4-dihydro- and 1,2-dihydroquinolizinium salts and the corresponding quinolizinium derivatives by an improved thermal oxidation in the presence of Pd/C without solvent. A comparative study showed that the quinolizinium system was obtained in better yields through the 3,4-dihydroquinolizinium route, thus allowing the synthesis of quinolizinium derivatives or improvements in the yields of some examples reported previously.

N-[2-(2-Pyridinyl)ethyl]benzamide compounds and their use as fungicides

Compound of general formula (I): Process for preparing this compound. Fungicidal composition comprising a compound of general formula (I). Method for treating plants by applying a compound of general formula (I) or a composition comprising it.