3884-34-2

Usage

Uses

Used in Medicinal Chemistry and Pharmaceutical Research:
4-(4-BROMOPHENYL)-2-HYDROXY-THIAZOLE is used as a chemical compound for its biological activity and potential as a therapeutic agent. It is studied for its applications in the development of new drugs and treatments.
Used in Organic Synthesis:
4-(4-BROMOPHENYL)-2-HYDROXY-THIAZOLE is used as a building block in the synthesis of other complex compounds. Its unique structure and functional groups make it a valuable component in the creation of novel organic molecules for various applications.

InChI:InChI=1/C9H6BrNOS/c10-7-3-1-6(2-4-7)8-5-13-9(12)11-8/h1-5H,(H,11,12)

Upstream product

• 65679-14-3 1-(4-bromophenyl)-2-thiocyanatoethanone 
• 333-20-0 potassium thioacyanate 
• 99-90-1 para-bromoacetophenone 
• 625-57-0 O-ethyl thiocarbamate 
• 99-73-0 para-bromophenacyl bromide 

Downstream Products

• 79328-26-0 4-(4-bromo-phenyl)-3-methyl-3H-thiazol-2-one 
• 79307-60-1 4-(4-Bromo-phenyl)-2-methoxy-thiazole 
• 127719-31-7 C₃₃H₃₀Br₂N₂O₇S₂ 

Relevant academic research and scientific papers

Synthesis of novel 1,3-thiazole-triazole and 1,3-thiazole-isoxazole hybrids

A focused library of thirteen compounds, 3-((1-benzyl-1H-l,2,3-triazol-4-yl)methyl)-4-arylthiazol-2(3H)-ones (6a-j) and 4-aryl-3-((3-aryhsoxazol-5-yl)methyl)thiazol-2(3H)-one hybrids has been synthesized. Their chemical structures have been confirmed by H

Tetrazolinone compound and application for same

Provided is a tetrazolinone compound given by formula (1) (wherein E represents the following group E16 or the like; Y represents -O-CH2- or the like; Q represents the following group Q46 or the like; R8 represents a C1-C6 alkyl group; R3, R30, and R31 may be the same or different, and represent hydrogen atoms or the like; A represents a C6-C16 aryl group or the like, optionally having one or more atoms or groups selected from the group P1; R5 represents a C1-C3 alkyl group; and X represents an oxygen or sulfur atom), and having exceptional efficacy in controlling harmful organisms.

TETRAZOLINONE COMPOUNDS AND ITS USE

The present invention provides a compound having an excellent efficacy for controlling pests. A tetrazolinone compound of a formula (1): [wherein, R1 represents an C6-C16 aryl group, an C1-C12 alkyl group, a C3-C12 cycloalkyl group or an adamantyl group, etc., which each optionally be substituted; R2 represents a hydrogen atom, an C1-C12 alkyl group, or a halogen atom, etc.; R4 and R5 represent independently of each other a hydrogen atom or an C1-C3 alkyl group, etc.; R6, R7, R8 and R9 represent independently of each other a hydrogen atom, a halogen atom, an C1-C12 alkyl group, a C1-C12 haloalkyl group, an C2-C12 alkenyl group, a C3-C12 cycloalkyl group, an C1-C12 alkoxy group or a C1-C12 haloalkoxy group, etc.; X and Y represent independently of each other a sulfur atom or an oxygen atom; Q represents an oxygen atom or a sulfur atom; and R10 represents an C1-C6 alkyl group, etc.] shows an excellent controlling efficacy on pests.

A correlative IR, MS, 1H, 13C and 15 NMR and theoretical study of 4-arylthiazol-2(3H)-ones

Sixteen 4-arylthiazol-2(3H)-ones (3) were synthesised by cyclisation of α-thiocyanatoacetophenones (1) in acid solution. They appear to prefer greatly the oxo tautomeric forms. In CCI4 solution an equilibrium between the free C=O bond and a "di

Hypervalent iodine in organic synthesis: One pot facile syntheses of α-thiocyanatoacetophenones, 2-hydroxy-, and 2-mercapto-4-arylthiazoles using [hydroxy (tosyloxy)iodo]benzene

Hypervalent iodine oxidation of acetophenones (1a-1e) with [hydroxy(tosyloxy)iodo]benze, followed by treatment with potassium thiocyanate offers a new facile synthesis of corresponding α-thiocyanatoacetophenones (3a-3e). Cyclization of 3a-3e, thus generated in situ, using AcOH/H2O and H2NC(S)NH2/HCl provides one pot facile syntheses of 2-hydroxy-, and 2-mercapto-4-arylthiazoles (4 and 5) respectively.