3884-34-2

Basic information

• Product Name: 4-(4-BROMOPHENYL)-2-HYDROXY-THIAZOLE
• Synonyms: SALOR-INT L499544-1EA;4-(4-BROMOPHENYL)THIAZOL-2-OL;4-(4-BROMOPHENYL)-2-HYDROXY-THIAZOLE;4-(4-Bromophenyl)-2-thiazolol;4-(4-bromophenyl)-3H-1,3-thiazol-2-one
• CAS NO: 3884-34-2
• Molecular Formula: C₉H₆BrNOS
• Molecular Weight: 256.12
• Mol File: 3884-34-2.mol
• Article Data: 5

Chemical Properties

• Melting Point: 248-252°C
• Appearance: /
• Density: 1.68g/cm³
• Refractive Index: 1.674
• CAS DataBase Reference: 4-(4-BROMOPHENYL)-2-HYDROXY-THIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(4-BROMOPHENYL)-2-HYDROXY-THIAZOLE(3884-34-2)
• EPA Substance Registry System: 4-(4-BROMOPHENYL)-2-HYDROXY-THIAZOLE(3884-34-2)

Safety Data

• Hazard Codes: Xn
• Statements: 22-37/38-41
• Safety Statements: 26-39
• RIDADR: UN 2811 6.1/PG 3
• WGK Germany: 3
• Hazardous Substances Data: 3884-34-2(Hazardous Substances Data)

Usage

General Description

4-(4-Bromophenyl)-2-hydroxy-thiazole, also known as 4-bromophenylthiazol-2-yl-4-formate, is a chemical compound with the molecular formula C11H8BrNO2S. It is a thiazole derivative with a bromophenyl group and a hydroxyl group attached to the thiazole ring. 4-(4-BROMOPHENYL)-2-HYDROXY-THIAZOLE has potential applications in medicinal chemistry and pharmaceutical research, as it exhibits biological activity and has been studied for its potential as a therapeutic agent. Additionally, it may also be used as a building block in organic synthesis for the preparation of other complex compounds. As with any chemical substance, proper handling and safety precautions should be taken when working with 4-(4-bromophenyl)-2-hydroxy-thiazole.

InChI:InChI=1/C9H6BrNOS/c10-7-3-1-6(2-4-7)8-5-13-9(12)11-8/h1-5H,(H,11,12)

Upstream product

• 65679-14-3 1-(4-bromophenyl)-2-thiocyanatoethanone 
• 333-20-0 potassium thioacyanate 
• 99-90-1 para-bromoacetophenone 
• 625-57-0 O-ethyl thiocarbamate 
• 99-73-0 para-bromophenacyl bromide 

Downstream Products

• 79328-26-0 4-(4-bromo-phenyl)-3-methyl-3H-thiazol-2-one 
• 79307-60-1 4-(4-Bromo-phenyl)-2-methoxy-thiazole 
• 127719-31-7 C₃₃H₃₀Br₂N₂O₇S₂ 

Relevant articles and documents

Synthesis of novel 1,3-thiazole-triazole and 1,3-thiazole-isoxazole hybrids

A focused library of thirteen compounds, 3-((1-benzyl-1H-l,2,3-triazol-4-yl)methyl)-4-arylthiazol-2(3H)-ones (6a-j) and 4-aryl-3-((3-aryhsoxazol-5-yl)methyl)thiazol-2(3H)-one hybrids has been synthesized. Their chemical structures have been confirmed by H

TETRAZOLINONE COMPOUNDS AND ITS USE

The present invention provides a compound having an excellent efficacy for controlling pests. A tetrazolinone compound of a formula (1): [wherein, R1 represents an C6-C16 aryl group, an C1-C12 alkyl group, a C3-C12 cycloalkyl group or an adamantyl group, etc., which each optionally be substituted; R2 represents a hydrogen atom, an C1-C12 alkyl group, or a halogen atom, etc.; R4 and R5 represent independently of each other a hydrogen atom or an C1-C3 alkyl group, etc.; R6, R7, R8 and R9 represent independently of each other a hydrogen atom, a halogen atom, an C1-C12 alkyl group, a C1-C12 haloalkyl group, an C2-C12 alkenyl group, a C3-C12 cycloalkyl group, an C1-C12 alkoxy group or a C1-C12 haloalkoxy group, etc.; X and Y represent independently of each other a sulfur atom or an oxygen atom; Q represents an oxygen atom or a sulfur atom; and R10 represents an C1-C6 alkyl group, etc.] shows an excellent controlling efficacy on pests.

Hypervalent iodine in organic synthesis: One pot facile syntheses of α-thiocyanatoacetophenones, 2-hydroxy-, and 2-mercapto-4-arylthiazoles using [hydroxy (tosyloxy)iodo]benzene

Hypervalent iodine oxidation of acetophenones (1a-1e) with [hydroxy(tosyloxy)iodo]benze, followed by treatment with potassium thiocyanate offers a new facile synthesis of corresponding α-thiocyanatoacetophenones (3a-3e). Cyclization of 3a-3e, thus generated in situ, using AcOH/H2O and H2NC(S)NH2/HCl provides one pot facile syntheses of 2-hydroxy-, and 2-mercapto-4-arylthiazoles (4 and 5) respectively.