38858-90-1

Basic information

• Product Name: 4-Methyl-3-nitro-1H-pyrazole
• Synonyms: 4-Methyl-3-nitro-1H-pyrazole;4-Methyl-3-nitropyrazole;1H-Pyrazole, 4-methyl-3-nitro-;4-methyl-3-nitro-2H-pyrazole;4-Methyl-5-nitro-pyrazole
• CAS NO: 38858-90-1
• Molecular Formula: C₄H₅N₃O₂
• Molecular Weight: 127.1014
• Mol File: 38858-90-1.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 317.2±22.0 °C(Predicted)
• Appearance: /
• Density: 1.426±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 9.27±0.50(Predicted)
• CAS DataBase Reference: 4-Methyl-3-nitro-1H-pyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methyl-3-nitro-1H-pyrazole(38858-90-1)
• EPA Substance Registry System: 4-Methyl-3-nitro-1H-pyrazole(38858-90-1)

Safety Data

• Hazardous Substances Data: 38858-90-1(Hazardous Substances Data)

Usage

Uses

4-Methyl-3-nitropyrazole is used in the synthesis of 4-(N-azolyl)-3,5-dinitropyrazoles.

InChI:InChI=1S/C4H5N3O2/c1-3-2-5-6-4(3)7(8)9/h2H,1H3,(H,5,6)

Upstream product

• 24086-18-8 3-iodo-4-methyl-1H-pyrazole 
• 7554-65-6 4-methyl-1H-pyrazole 

Downstream Products

• 1246855-83-3 1-(3,5-dinitrophenyl)-4-methyl-3-nitropyrazole 
• 26956-09-2 1,4-dimethyl-3-nitropyrazole 

Relevant articles and documents

INHIBITORS OF NECROPTOSIS

This invention relates to compounds of Formula (I) and salts, solvates, prodrugs, tautomers, N-oxides, stereoisomers, polymorphs and physiologically functional derivatives thereof. Also disclosed are methods of use of Formula (I), including in the inhibition of necroptosis and treatment of associated diseases, conditions and/or disorders.

Faujasite catalyzed nitrodeiodination of iodopyrazoles

Nitrodeiodination of iodopyrazoles using nitric acid/Faujasite has been investigated. The present procedure is simple, rapid and convenient and requires no sulfuric acid or oleum and may be applied for the synthesis of several nitropyrazoles in good yield

Silica-sulfuric acid catalyzed nitrodeiodination of iodopyrazoles

We report here the synthesis of nitropyrazoles in good to excellent yields from iodopyrazoles over silica-sulfuric acid catalyst for the first time. The present procedure require less acid, offers a simplified workup procedure, and may be applied for the