388606-35-7

Upstream product

• 433330-76-8 6-(4-methoxy-phenyl)-5-phenyl-4,5-dihydro-2H-pyridazin-3-one 
• 103-80-0 phenylacetyl chloride 
• 93098-10-3 ethyl 3-(4-methoxybenzoyl)-3-phenylpropionate 
• 101597-51-7 4-(4-methoxyphenyl)-4-oxo-3-phenylbutyric acid 
• 1023-17-2 4-methoxyphenyl benzyl ketone 
• 103-82-2 phenylacetic acid 
• 225666-34-2 6-(4-Methoxyphenyl)-5-phenyl-2H-pyridazin-3-one 

Relevant academic research and scientific papers

PHENYLPYRIDAZINE DERIVATIVES AND DRUGS CONTAINING THE SAME

Phenylpyridazine compounds represented by the following formula (I): (wherein R1 represents a substituted or unsubstituted phenyl or a a substituted or unsubstituted pyridyl; R2 represents a lower alkoxy group, a lower alkylthio group, a lower alkylsufiny

Phenylpyridazine compounds and medicines containing the same

Phenylpyridazine compounds represented by the following formula (I): are provided, wherein R1, R2, R3, R4, and n are as defined herein having excellent inhibitory activity against interleukin-1β production, and

Mono- and di-substituted 5,6-diphenyl-3-alkylaminopyridazines active as ACAT inhibitors

A series of mono- or di-para-substituted 5,6-diphenyl-3-alkylaminopyridazines were synthesized and their inhibitory activity against acyl-CoA:cholesterol acyltransferase (ACAT) was tested on the enzyme prepared from rat liver microsomes. The compound which combines a chlorine atom on the 6-phenyl ring and a n-hexylamino chain showed a significant enhancement of activity with respect to the unsubstituted derivative. Attempts to correlate the activity of the compounds to their structural features, also through theoretical calculations, are reported.