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Ethyl 3-fluoro-2-iodobenzoate is an organic chemical compound with the molecular formula C9H8FIO2. It is a colorless to pale yellow crystalline solid that is soluble in organic solvents. ethyl 3-fluoro-2-iodobenzoate is characterized by the presence of a fluorine atom at the 3rd position and an iodine atom at the 2nd position on the benzene ring, with an ethyl ester group attached to the carboxylic acid functionality. Ethyl 3-fluoro-2-iodobenzoate is used as an intermediate in the synthesis of pharmaceuticals and other organic compounds, particularly in the production of certain anti-inflammatory and analgesic drugs. Its unique structure with both fluorine and iodine atoms makes it a valuable building block for the development of new molecules with specific properties.

389-43-5

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389-43-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 389-43-5 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,8 and 9 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 389-43:
(5*3)+(4*8)+(3*9)+(2*4)+(1*3)=85
85 % 10 = 5
So 389-43-5 is a valid CAS Registry Number.

389-43-5Downstream Products

389-43-5Relevant academic research and scientific papers

One-Pot C-H Arylation/Lactamization Cascade Reaction of Free Benzylamines

Chand-Thakuri, Pratibha,Landge, Vinod G.,Kapoor, Mohit,Young, Michael C.

, p. 6626 - 6644 (2020/07/14)

An efficient method has been developed for the synthesis of seven-membered biaryl lactams involving Pd-catalyzed, native amine-directed, ortho-arylation of benzylamines followed by in situ lactamization. This cascade sequence is enabled by the use of 2-iodobenzoates, which facilitates C-H arylation from the free amine under conditions that typically require an improved directing group approach. This reaction is characterized by a broad substrate scope with good functional group tolerance. The need for an ester versus carboxylic acid-functionalized coupling partner is also explored, as is the potential for synthesizing eight-membered biaryl lactams. Various applications are also investigated, including access to the aza-brassinolide core.

BISAMID-ZINKBASEN

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Page/Page column 7-8, (2010/07/04)

The present invention relates to zinc amide bases of the general formula (I) [in-line-formulae](R1R2N)2—Zn.aMgX12.bLiX2??(I)[/in-line-formulae] wherein R1 and R2 are e

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