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Pyrrolidine, 1,1'-[1,4-phenylenebis(methylene)]bis- is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

39022-99-6

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39022-99-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 39022-99-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,0,2 and 2 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 39022-99:
(7*3)+(6*9)+(5*0)+(4*2)+(3*2)+(2*9)+(1*9)=116
116 % 10 = 6
So 39022-99-6 is a valid CAS Registry Number.

39022-99-6Downstream Products

39022-99-6Relevant articles and documents

Symmetrical bis-tertiary amines as novel CXCR4 inhibitors

Bai, Renren,Liang, Zhongxing,Yoon, Younghyoun,Liu, Shuangping,Gaines, Theresa,Oum, Yoonhyeun,Shi, Qi,Mooring, Suazette Reid,Shim, Hyunsuk

, p. 340 - 350 (2016)

CXCR4 inhibitors are promising agents for the treatment of cancer metastasis and inflammation. A series of novel tertiary amine derivatives targeting CXCR4 were designed, synthesized, and evaluated. The central benzene ring linker and side chains were mod

BIS-AMINES, COMPOSITIONS, AND USES RELATED TO CXCR4 INHIBITION

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Page/Page column 65, (2017/02/09)

This disclosure relates bis-amine compounds disclosed herein and uses related to CXCR4 inhibition. In certain embodiments, the compounds have formula (I), salts, derivatives, and prodrugs thereof wherein, A is a bridging aryl or heterocyclyl and R1 and R2 are further disclosed herein. In certain embodiments, the disclosure contemplates pharmaceutical compositions comprising compounds disclosed herein. In certain embodiments, the disclosure relates to methods of treating or preventing CXCR4 related diseases or conditions by administering an effective amount of a compound disclosed herein to a subject in need thereof.

Novel bis-piperidinium and bis-pyrrolidinium compounds as versatile phase-transfer catalysts

Saif, Muhammad Jawwad,Anwar, Jamil,Munawar, Munawar Ali,Kashif, Muhammad,Asghar, Muhammad Imran

experimental part, p. 133 - 145 (2010/12/19)

Syntheses and applications of new bis-piperidinium and bis-pyrrolidinium compounds as effective two-center phase-transfer catalysts are presented. Applications of these catalysts have been explored in etherification and N-alkylation reactions, and comparisons between these catalysts and traditional phase-transfer catalysts such as cetyltrimethylammonium bromide (CTAB) and 1-ethyl-3-methylimidazolium chloride (emim+Cl-) are presented. ARKAT USA, Inc.

An efficient synthesis of nitrogen heterocycles by Cp*Ir-catalyzed N-cycloalkylation of primary amines with diols

Fujita, Ken-ichi,Fujii, Takeshi,Komatsubara, Atsuo,Enoki, Youichiro,Yamaguchi, Ryohei

, p. 673 - 682 (2008/09/18)

A new efficient method for the N-cycloalkylation of primary amines with diols catalyzed by a Cp*Ir complex have been developed. A variety of five-, six-, and seven-membered cyclic amines are synthesized in good to excellent yields in environmentally benign and atom economical manner with the formation of only water as a coproduct. A large scale synthesis of N-benzylpiperidine and a two-step asymmetric synthesis of (S)-2-phenylpiperidine using (R)-1-phenylethylamine as a starting primary amine have been also achieved.

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