390748-01-3

Upstream product

• 108-24-7 acetic anhydride 
• 24424-99-5 di-tert-butyl dicarbonate 
• 98-09-9 benzenesulfonyl chloride 
• 566905-25-7 methyl 4-hydroxy-1-phenylsulfonyl-1,2,5,6-tetrahydro-3-pyridinecarboxylate 
• 390747-97-4 7-benzenesulfonyl-2,7-diaza-spiro[4.5]decane-1,10-dione 
• 566905-26-8 methyl 3-allyl-4-oxo-1-(phenylsulfonyl)-3-piperidinecarboxylate 
• 390747-95-2 8-benzenesulfonyl-6-(2-oxo-ethyl)-1,4-dioxa-8-aza-spiro[4.5]decane-6-carboxylic acid methyl ester 
• 679841-13-5 12-benzenesulfonyl-1,4-dioxa-8,12-diaza-dispiro[4.0.4.4]tetradecan-7-one 
• 390747-94-1 methyl 6-allyl-8-(phenylsulfonyl)-1,4-dioxa-8-azaspiro[4.5]decane-6-carboxylate 
• 390747-99-6 7-benzenesulfonyl-1-oxo-10-trifluoromethanesulfonyloxy-2,7-diaza-spiro[4.5]dec-9-ene-2-carboxylic acid tert-butyl ester 
• 390747-96-3 12-benzenesulfonyl-8-(4-methoxy-benzyl)-1,4-dioxa-8,12-diaza-dispiro[4.0.4.4]tetradecan-7-one 
• 390748-00-2 7-benzenesulfonyl-10-furan-3-yl-1-oxo-2,7-diaza-spiro[4.5]dec-9-ene-2-carboxylic acid tert-butyl ester 
• 390747-98-5 7-benzenesulfonyl-1,10-dioxo-2,7-diaza-spiro[4.5]decane-2-carboxylic acid tert-butyl ester 

Relevant academic research and scientific papers

Synthetic approach towards nakadomarin A: Efficient synthesis of the central tetracyclic core

An efficient synthesis of the tetracyclic core of nakadomarin A was accomplished starting from methyl 4-oxo-3-piperidinecarboxylate. The key steps were intramolecular cyclization of furan to N-acyliminium ions to construct the strained central cyclopenten