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CAS

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3910-11-0

Phenyl hydrogen phosphorofluoridate, also known as phenyl fluorophosphite or PFP, is a highly toxic organophosphorus compound with the chemical formula C6H5POF2. It is a colorless, oily liquid that is soluble in organic solvents and has a strong, pungent odor. PFP is a potent inhibitor of acetylcholinesterase, an enzyme responsible for breaking down the neurotransmitter acetylcholine in the nervous system. This inhibition leads to an accumulation of acetylcholine, causing overstimulation of the nervous system and potentially leading to seizures, respiratory failure, and death. Due to its high toxicity and potential use as a chemical warfare agent, PFP is classified as a Schedule 1 substance under the Chemical Weapons Convention. It is important to handle PFP with extreme caution and in accordance with strict safety protocols.

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  • 3910-11-0 Structure

  • Basic information

    1. Product Name: phenyl hydrogen phosphorofluoridate
    2. Synonyms: phenyl hydrogen phosphorofluoridate
    3. CAS NO:3910-11-0
    4. Molecular Formula:
    5. Molecular Weight: 176.084
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 3910-11-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: phenyl hydrogen phosphorofluoridate(CAS DataBase Reference)
    10. NIST Chemistry Reference: phenyl hydrogen phosphorofluoridate(3910-11-0)
    11. EPA Substance Registry System: phenyl hydrogen phosphorofluoridate(3910-11-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 3910-11-0(Hazardous Substances Data)

3910-11-0 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 3910-11-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,9,1 and 0 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 3910-11:
(6*3)+(5*9)+(4*1)+(3*0)+(2*1)+(1*1)=70
70 % 10 = 0
So 3910-11-0 is a valid CAS Registry Number.

3910-11-0Downstream Products

3910-11-0Relevant articles and documents

Nucleophilic 18F-fluorination of phosphorofluoridates and phosphonofluoridic acids via imidazole-activated precursors

Mou, Zhaobiao,Chen, Xueyuan,Wang, Chao,Wang, Tao,Yang, Hongzhang,Li, Zijing

, (2021/03/03)

18F-Labeled organofluorophosphates are important radiosynthons that have only been previously accessible via 18/19F-isotope-exchange with limited molar activities. Herein, a novel 18F-fluorination methodology has been developed to prepare 18F-labeled phosphorofluoridates and phosphonofluoridic acids via the [18F]F? nucleophilic substitution of imidazole-activated precursors. The efficient one-step 18F-fluorination affords stable products in the presence of Zn(Ⅱ) with high radiochemical yields and high molar activities. This 18F-fluorination method could be used to prepare various phosphorofluoridate and phosphonofluoridic acid analogs for use as 18F-radiosynthons and potential positron emission tomography tracers.

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