Welcome to LookChem.com Sign In|Join Free

CAS

  • or

701-64-4

Post Buying Request

701-64-4 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

701-64-4 Usage

Uses

Phenyl Phosphate can be used to stain membranes and other biological structures.

Definition

ChEBI: An aryl phosphate resulting from the mono-esterification of phosphoric acid with phenol.

Synthesis Reference(s)

Chemical and Pharmaceutical Bulletin, 34, p. 3121, 1986 DOI: 10.1248/cpb.34.3121Journal of the American Chemical Society, 77, p. 3524, 1955 DOI: 10.1021/ja01618a029

Check Digit Verification of cas no

The CAS Registry Mumber 701-64-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 7,0 and 1 respectively; the second part has 2 digits, 6 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 701-64:
(5*7)+(4*0)+(3*1)+(2*6)+(1*4)=54
54 % 10 = 4
So 701-64-4 is a valid CAS Registry Number.
InChI:InChI=1/C6H7O4P.Mg/c7-11(8,9)10-6-4-2-1-3-5-6;/h1-5H,(H2,7,8,9);/q;+2/p-2

701-64-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name phenyl phosphate

1.2 Other means of identification

Product number -
Other names PHENYLPHOSPHORIC ACID

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Paint additives and coating additives not described by other categories
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:701-64-4 SDS

701-64-4Relevant articles and documents

Biologically reversible phosphate-protective groups

Farquhar,Srivastva,Kuttesch,Saunders

, p. 324 - 325 (1983)

-

Model studies indicate that copper phenanthroline induces direct strand breaks via β-elimination of the 2'-deoxyribonolactone intermediate observed in enediyne mediated DNA damage [2]

Chen,Greenberg

, p. 3815 - 3816 (1998)

-

Organophosphorous phenyl phosphates: Synthesis, dye/protein interactions and antimicrobial evaluation

Ameta, Rakesh Kumar,Duan, Yongtao,Koshti, Rohit R.,Muddassir, Mohd.,Patel, Amee S.,Trivedi, Nidhi S.,Vyas, Akshay

, (2021/01/09)

A series of Phenyl Phosphates (PPs) has been synthesized and characterized with FTIR spectroscopy. PPs, the product of the reaction of phenol and phosphoryl chloride followed by hydrolysis having larger number of hydrophilic hydroxyl groups, used for the dye interaction and antimicrobial activities. Interaction of PPs with 1,2-diphenyldiazene and 4-(phenyldiazene)phenol were studied through UV/ Vis method where observed hypochromic effect has revealed the dye adsorption property of PPs. Similarly PPs have shown the interaction with bovine serum and human serum albumins where the weaker interaction observed with later. Antimicrobial in vitro evaluation has been assessed on the basis of zone of inhibition with six bacterial (gram +ve and –ve) strains. Since PPs were found very active so minimal inhibitory concentration (MIC) analysis was done where all PPs have shown MIC less than 5 μg/mL. Due to high number of hydroxyl groups PPs have shown good interactions with biomolecules and cell wall of bacteria therefore this impression has predicted their future in medicinal field.

Transition States and Control of Substrate Preference in the Promiscuous Phosphatase PP1

Chu, Yuan,Williams, Nicholas H.,Hengge, Alvan C.

, p. 3923 - 3933 (2017/08/07)

Catalytically promiscuous enzymes are an attractive frontier for biochemistry, because enzyme promiscuities not only plausibly explain enzyme evolution through the mechanism of gene duplication but also could provide an efficient route to changing the catalytic function of proteins by mimicking this evolutionary process. PP1γ is an effectively promiscuous phosphatase for the hydrolysis of both monoanionic and dianionic phosphate ester-based substrates. In addition to its native phosphate monoester substrate, PP1γ catalyzes the hydrolysis of aryl methylphosphonates, fluorophosphate esters, phosphorothioate esters, and phosphodiesters, with second-order rate accelerations that fall within the narrow range of 1011-1013. In contrast to the different transition states in the uncatalyzed hydrolysis reactions of these substrates, PP1γ catalyzes their hydrolysis through similar transition states. PP1γ does not catalyze the hydrolysis of a sulfate ester, which is unexpected. The PP1γ active site is tolerant of variations in the geometry of bound ligands, which permit the effective catalysis even of substrates whose steric requirements may result in perturbations to the positioning of the transferring group, both in the initial enzyme-substrate complex and in the transition state. The conservative mutation of arginine 221 to lysine results in a mutant that is a more effective catalyst toward monoanionic substrates. The surprising conversion of substrate preference lends support to the notion that mutations following gene duplication can result in an altered enzyme with different catalytic capabilities and preferences and may provide a pathway for the evolution of new enzymes.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 701-64-4