39119-35-2Relevant academic research and scientific papers
Synthesis of 5-Amino-2,5-dihydro-1H-benzo[b]azepines Using a One-Pot Multibond Forming Process
Sharif, Salaheddin A. I.,Calder, Ewen D. D.,Delolo, Fábio G.,Sutherland, Andrew
, p. 6697 - 6706 (2016/08/16)
Rapid access to allylic trichloroacetimidates bearing a 2-allylaminoaryl group from readily available 2-iodoanilines combined with a one-pot multibond forming process has allowed the efficient synthesis of a series of 5-amino-2,5-dihydro-1H-benzo[b]azepin
Ir-Catalyzed C?H Amidation of Aldehydes with Stoichiometric/Catalytic Directing Group
Zhang, Yun-Fei,Wu, Bin,Shi, Zhang-Jie
, p. 17808 - 17812 (2016/11/28)
Ir-catalyzed sp2C?H amidation of aldehydes with various anilines as stoichiometric or catalytic directing groups was accomplished. A wide range of substrates were selectively amidated in good to excellent yields with broad functional group tolerance. The iridacycle complexes were isolated, characterized, and proved as key intermediates. Kinetic studies and Hammett plots provided detailed understandings of this amidation. According to the mechanism, the electron-rich ArSO2N3was proved effective for intermolecular sp3C?H amidation.
