3915-73-9Relevant academic research and scientific papers
Modified steroids 103. Splitting of the 17-C-N bond of 16,17α-epimino-20-ketgsteroids and their 20-hydrazones by reaction with thioacetic acid
Kamernitskii,Turupa,Fadeeva,Pavlov
, p. 825 - 831 (1979)
1. The reactions of 16,17 α-eplminopregn-5-en-3 β-ol-20-one and its 20-carbethoxyhydrazone with thioacetic acid proceed with different stereochemical direction of scission of the aziridine ring at the tertiary 17-C atom. Schemes to explain the differences are proposed. 2. A new class of heterocyclic compounds, 2′-methyl-[16,17α-d]-thiazoline 20-ketosteroids, has been obtained.
A simple procedure for selective reduction of α,β-unsaturated carbonyl compounds using Al-NiCl2 system
Hazarika,Barua
, p. 6567 - 6570 (2007/10/02)
A combination of aluminium and nickel chloride in THF has been shown to effect the selective reduction of the olefinic double bond of the α-enone system. Isolated double bonds and aliphatic carbonyls remain unaffected under these conditions. However, aromatic aldehydes and ketones are converted to the corresponding hydroxy compounds by this system in good yields.
