39178-28-4

Usage

General Description

2-(1-methylpyrrolidin-2-ylidene)-1-phenylethanone, also known as MDPHP, is a synthetic cathinone and a derivative of pyrovalerone. It is a psychoactive designer drug that is often sold online under the guise of being a research chemical. MDPHP is known for its stimulant and entactogenic effects, and it is often used as a recreational drug. However, it can also have dangerous and unpredictable effects, including paranoia, hallucinations, and potential for addiction. MDPHP is a controlled substance in many countries and is illegal to manufacture, distribute, or possess without proper authorization.

Upstream product

• 22650-95-9 3,4-dihydro-1-methyl-5-<(2-oxo-2-phenylethyl)thio>-2H-pyrrolium bromide 
• 872-50-4 1-methyl-pyrrolidin-2-one 
• 10441-57-3 1-methyl-pyrrolidine-2-thione 
• 25355-40-2 3,4-dihydro-1-methyl-2-(methylthio)-5H-pyrrolium iodide 
• 98-86-2 acetophenone 
• 614-20-0 3-oxo-3-phenylpropionic acid 

Downstream Products

• 76103-58-7 2-(1-methylpyrrolidin-2-yl)-1-phenylethanon 

Relevant academic research and scientific papers

Synthesis of Unsymmetrical Functionalised Organic Sulphides

Acyclic thioiminium salts and the condensed thiazolium salts in the presence of aqueous sodium hydroxide as such or under base catalyzed phase transfer catalysis conditions react with appropiate organic halides to provide corresponding unsymmetrical functionalized organic sulphides.With aqueous sodium hydroxide, thioiminium salts provide the disulphides corresponding to incipient thiol.

Synthesis of Functionalised Enamines from α-Thioiminium Salts and Active Methylene Compounds

Monoprotic and nonprotic α-thioiminium salts react with active methylene compounds under solid liquid phase transfer catalysis (PTC) to give the corresponding enamines in good yields.

THE APPLICATION OF THE SULPHIDE CONTRACTION TO THE SYNTHESIS OF SOME SIMPLE PYRROLIDINE ALKALOIDS

The alkaloids (+/-)-hygrine, (+/-)-dehydrodarlinine, (+/-)-dehydrodarlingianine, and (+/-)-N-methylruspolinone have been synthesised by selective reduction of vinylogous amides formed by sulphide contraction of the salts prepared by reaction of N-methyl-2

Methods for Converting N-Alkyl Lactams to Vinylogous Urethanes and Vinylogous Amides via (Methylthio)alkylideniminium Salts

Treatment of enolizable (methylthio)alkylideniminium salts with active methylene compounds under basic conditions gives Knoevenagel-type adducts in excellent yields.Attempts to convert several of these adducts to vinylogous urethanes and vinylogous amides met with varied success.One-pot preparations of vinylogous urethanes and vinylogous amides from (methylthio)alkylideniminium salts and selected active methylene compounds are also described.