3919-73-1Relevant academic research and scientific papers
Asymmetric synthesis of polyhydroxylated N -alkoxypiperidines by ring-closing double reductive amination: Facile preparation of isofagomine and analogues
Malik, Gaelle,Guinchard, Xavier,Crich, David
supporting information; experimental part, p. 596 - 599 (2012/02/16)
A de novo synthesis of novel polyhydroxylated N-alkoxypiperidines based on the ring-closing double reductive amination of 1,5-dialdehydes, obtained by oxidative cleavage of cyclopentene derivatives, with O-substituted hydroxylamines is reported. Isofagomine was accessed by cleavage of the N-O bond of an N-alkoxypiperidine.
Design, Synthesis, and Biological Evaluation of Thio-Containing Compounds with Serum HDL-Cholesterol-Elevating Properties
Elokdah, Hassan,Sulkowski, Theodore S.,Abou-Gharbia, Magid,Butera, John A.,Chai, Sie-Yearl,McFarlane, Geraldine R.,McKean, Mar-Lee,Babiak, John L.,Adelman, Steven J.,Quinet, Elaine M.
, p. 681 - 695 (2007/10/03)
A novel series of substituted sulfanyldihydroimidazolones (1) that modulates high-density lipoprotein cholesterol (HDL-C) has been reported to have HDL-elevating properties in several animal models. Concerns about the chemical and metabolic stability of 1
Symmetrical O-substituted dioximes of benzo-fused β-diketocyclo-alkylenes, the processes for their preparation and their application as drugs
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, (2008/06/13)
Drugs with high anticonvulsant and analgesic activities constituted by symmetrical β-dialkoxyiminocycloalklene derivatives in which the imine double bonds are conjugated with the cyclic double bond or bonds belonging to one or more fused benzene rings. They correspond to the general formula I: STR1
