39190-96-0

Basic information

• Product Name: N-(4-METHYLBENZYL)-N-PROPYLAMINE
• Synonyms: N-(4-Methylbenzyl)propan-1-aMine
• CAS NO: 39190-96-0
• Molecular Formula: C₁₁H₁₇N
• Molecular Weight: 163.2594
• Mol File: 39190-96-0.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 234.6 °C at 760 mmHg
• Flash Point: 94.8 °C
• Appearance: /
• Density: 0.905 g/cm³
• Vapor Pressure: 0.0524mmHg at 25°C
• Refractive Index: 1.504
• CAS DataBase Reference: N-(4-METHYLBENZYL)-N-PROPYLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-METHYLBENZYL)-N-PROPYLAMINE(39190-96-0)
• EPA Substance Registry System: N-(4-METHYLBENZYL)-N-PROPYLAMINE(39190-96-0)

Safety Data

• Hazardous Substances Data: 39190-96-0(Hazardous Substances Data)

Usage

General Description

N-(4-methylbenzyl)-N-propylamine is a chemical compound with the molecular formula C13H19N. It is a primary aliphatic amine with a benzyl group and a propyl group attached to the nitrogen atom. N-(4-METHYLBENZYL)-N-PROPYLAMINE is commonly used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. It can also be used as a reagent in organic synthesis to introduce the benzyl and propyl functional groups. N-(4-methylbenzyl)-N-propylamine is a clear, colorless to light yellow liquid with a faint odor, and it has a relatively high boiling point, making it useful in a variety of chemical reactions and processes. It is important to handle this chemical with care, as it may be irritating to the skin, eyes, and respiratory system.

InChI:InChI=1/C11H17N/c1-3-8-12-9-11-6-4-10(2)5-7-11/h4-7,12H,3,8-9H2,1-2H3

Upstream product

• 107-10-8 propylamine 
• 104-87-0 4-methyl-benzaldehyde 
• 71-23-8 propan-1-ol 
• 104-84-7 para-methylbenzylamine 
• 154777-49-8 N-(p-methylbenzylidene)cyclopropylamine 
• 70894-72-3 N-(p-methylbenzyl)cyclopropylamine 
• 104-82-5 4-Methylbenzyl chloride 
• 104-81-4 4-Methylbenzyl bromide 
• 138710-10-8 N-(benzenesulfenyl)-N-(p-methylbenzyl)cyclopropylamine 

Relevant articles and documents

Simple Metal-Free Direct Reductive Amination Using Hydrosilatrane to Form Secondary and Tertiary Amines

This work describes the use of cheap, safe, and easy-to-handle hydrosilatrane as the reductant in direct reductive amination reactions. This efficient method enables a facile, metal-free access to secondary and tertiary amines from a wide range of aldehydes and ketones, with the synthesis of tertiary amines requiring no additives at all. This reaction demonstrates excellent functional group tolerance, chemoselectivity, and scalability. (Figure presented.).

HETEROCYCLIC DERIVATIVE HAVING INHIBITORY ACTIVITY ON TYPE-I 11 -HYDROXYSTEROID DEHYDROGENASE

Disclosed is a compound which is useful as an 11β-hydroxysteroid dehydrogenase type 1 inhibitor. A compound represented by the formula: its pharmaceutically acceptable salt, or a solvate thereof, wherein X is O or S, a broken line and a wavy line represent the presence or the absence of a bond, (i) when a broken line represents the presence of a bond, a wavy line represents the absence of a bond, R2 and R3 are each independently hydrogen, halogen, cyano, hydroxy, carboxy, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl or the like, (ii) when a broken line represents the absence of a bond, a wavy line represents the presence of a bond, R1 and R4 are each independently hydrogen, halogen or the like, R2 and R3 are each independently hydrogen, halogen, cyano, hydroxy, carboxy, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl or the like, and R5 and R6 are each independently hydrogen, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl or the like.

Preparation of benzolactams by Pd(OAC)2-catalyzed direct aromatic carbonylation

We developed a new method for Pd(II)-catalyzed direct aromatic carbonylation in a phosphine-free catalytic system using Pd(OAc)2 and Cu(OAc)2 in an atmosphere of CO gas containing air. The carbonylation proceeded with ortho-palladation, inducing a remarkable site selectivity to afford a variety of five- or six-membered benzolactams from secondary ω-arylalkylamines, such as N-alkylbenzylamines or N-alkylphenethylamines. Copyright