391902-03-7

Basic information

• Product Name: tert-butyl (2 S)-3-[4-(benzyloxy)phenoxy]-2-hydroxypropyl[4-(methylamino)phenethyl]carbamate
• CAS NO: 391902-03-7
• Molecular Weight: 506.642
• Mol File: 391902-03-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl (2 S)-3-[4-(benzyloxy)phenoxy]-2-hydroxypropyl[4-(methylamino)phenethyl]carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (2 S)-3-[4-(benzyloxy)phenoxy]-2-hydroxypropyl[4-(methylamino)phenethyl]carbamate(391902-03-7)
• EPA Substance Registry System: tert-butyl (2 S)-3-[4-(benzyloxy)phenoxy]-2-hydroxypropyl[4-(methylamino)phenethyl]carbamate(391902-03-7)

Safety Data

• Hazardous Substances Data: 391902-03-7(Hazardous Substances Data)

Upstream product

• 321574-99-6 (2S)-1-[(4-aminophenethyl)amino]-3-[4-(benzyloxy)phenoxy]-2-propanol 
• 103-16-2 4-Benzyloxyphenol 
• 13472-00-9 p-Aminophenethylamine 
• 74-83-9 methyl bromide 
• 321575-01-3 tert-butyl 4-aminophenethyl{(2S)-3-[4-(benzyloxy)phenoxy]-2-hydroxypropyl}carbamate 
• 122797-04-0 (S)-{[4-(Phenylmethoxy)phenoxy]methyl}-oxirane 

Downstream Products

• 321575-25-1 5-[(4-{2-[(2 S)-3-(4-Benzyloxy-phenoxy)-2-hydroxy-propylamino]-ethyl}-phenyl)-methyl-amino]-thiazolidine-2,4-dione 

Relevant articles and documents

Potent, selective aminothiazolidinediones agonists of the human β3 Adrenergic receptor

A cloned human β3 adrenergic receptor assay was used to identify potent and selective β3 agonists. The thiazolidinedione moiety has been identified as a new pharmacophore for the human β3 adrenergic receptor. The versatility of the thiazolidinedione pharmacophore was demonstrated in both the arylethanolamine and phenylpropanolamine families of β3 agonists, where potent and selective compounds have been synthesized. Thiazolidinedione 20, a potent and selective human β3 agonist, increased thermogenesis and lowered plasma glucose levels in the db/db mice.