392-14-3Relevant articles and documents
Cobalt(II)-catalyzed regioselective C-H halogenation of anilides
Li, Ze-lin,Sun, Kang-kang,Cai, Chun
, p. 5433 - 5440 (2018)
A cobalt-catalyzed regioselective C-H halogenation methodology is reported herein. The highlight of this work is the highly selective C-H functionalization of anilides, which results in high-yielding, versatile, and practical halogenated products. Thereby, brominations, chlorinations and iodinations of many electron-rich and electron-deficient anilides were achieved in a highly selective fashion. Mechanistic studies with respect to the pathway of the reaction are also described.