39200-49-2 Usage
Uses
Used in Pharmaceutical Industry:
(3S)-3-benzyl-7-chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one is used as a potential therapeutic agent for the treatment of anxiety and insomnia. Its chemical structure and benzodiazepine classification suggest that it may possess anxiolytic and sedative properties, which could be beneficial in managing these conditions. However, further research and testing are required to confirm its specific pharmacological effects and therapeutic potential.
Used in Research and Development:
(3S)-3-benzyl-7-chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one is also used in the research and development of new drugs and therapies. Its structural similarity to other benzodiazepines makes it a valuable tool for studying the mechanisms of action and potential side effects of these drugs. Additionally, it may serve as a starting point for the design and synthesis of novel benzodiazepine-based medications with improved efficacy and reduced side effects.
Used in Neurological Applications:
(3S)-3-benzyl-7-chloro-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one may be used as a potential treatment for neurological disorders such as seizures, due to the known sedative and anxiolytic properties of benzodiazepines. Its potential use in this application is based on the ability of benzodiazepines to modulate the activity of gamma-aminobutyric acid (GABA) receptors in the central nervous system, which play a crucial role in controlling neuronal excitability and seizure activity.
Check Digit Verification of cas no
The CAS Registry Mumber 39200-49-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,2,0 and 0 respectively; the second part has 2 digits, 4 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 39200-49:
(7*3)+(6*9)+(5*2)+(4*0)+(3*0)+(2*4)+(1*9)=102
102 % 10 = 2
So 39200-49-2 is a valid CAS Registry Number.
39200-49-2Relevant academic research and scientific papers
An Atom-Economical Method to Prepare Enantiopure Benzodiazepines with N-Carboxyanhydrides
Fier, Patrick S.,Whittaker, Aaron M.
supporting information, p. 1454 - 1457 (2017/03/23)
The development of a rapid, one-pot synthesis of diazepinones with simple reagents is described. N-Carboxyanhydrides (NCAs) are employed as amino acid building blocks that react with o-ketoanilines sequentially as electrophiles and nucleophiles to form diazepinones with water and carbon dioxide as byproducts. Notably, these reactions enable the coupling of stereodefined amino acid derived NCAs without racemization. This method is demonstrated by an improved synthesis of a key intermediate toward a bromodomain and extra-terminal (BET) bromodomain inihibitor.
Discrimination between enantiomers of structurally related molecules: Separation of benzodiazepines by molecularly imprinted polymers
Hart, Bradley R.,Rush, Daniel J.,Shea, Kenneth J.
, p. 460 - 465 (2007/10/03)
Molecular imprinting has been used to create synthetic receptor sites for a series of chiral benzodiazepines. A detailed HPLC analysis of binding properties using molecularly imprinted polymers (MIPs) as the stationary phase showed that binding, as measur
