39206-70-7 Usage
Uses
Used in Pharmaceutical Industry:
Etodolac is used as an analgesic and anti-inflammatory agent for the treatment of conditions such as osteoarthritis and rheumatoid arthritis. It is effective in managing the pain and inflammation associated with these conditions due to its ability to inhibit prostaglandin production.
Used in Oral Administration:
Etodolac is typically administered orally and is available in various forms, including tablets and capsules, for therapeutic use. This mode of administration allows for convenient and effective treatment of the targeted conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 39206-70-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,2,0 and 6 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 39206-70:
(7*3)+(6*9)+(5*2)+(4*0)+(3*6)+(2*7)+(1*0)=117
117 % 10 = 7
So 39206-70-7 is a valid CAS Registry Number.
InChI:InChI=1/C16H13ClO3/c17-13-8-6-11(7-9-13)14(16(19)20)10-15(18)12-4-2-1-3-5-12/h1-9,14H,10H2,(H,19,20)
39206-70-7Relevant academic research and scientific papers
Formation of γ-oxoacids and 1 H-pyrrol-2(5 H)-ones from α,β-unsaturated ketones and ethyl nitroacetate
Aginagalde, Maialen,Bello, Tamara,Masdeu, Carme,Vara, Yosu,Arrieta, Ana,Cossio, Fernando P.
experimental part, p. 7435 - 7438 (2010/12/25)
Michael addition of ethyl nitroacetate on α,β-unsaturated ketones followed by Nef oxidation under hydrolytic conditions yields γ-oxoacids instead of the corresponding α,δ-dioxoesters. A concerted decarboxylation step is proposed on the basis of computational results. Finally, conversion of the γ-ketoacids thus prepared into 1H-pyrrol-2(5H)-ones by reaction with primary amines under Paal-Knorr conditions is also reported.