392670-36-9Relevant academic research and scientific papers
Pyrrolidinyl-sulfamide derivatives as a new class of bifunctional organocatalysts for direct asymmetric Michael addition of cyclohexanone to nitroalkenes
Chen, Jia-Rong,Fu, Liang,Zou, You-Quan,Chang, Ning-Jie,Rong, Jian,Xiao, Wen-Jing
supporting information; experimental part, p. 5280 - 5287 (2011/08/07)
A series of chiral pyrrolidinyl-sulfamide derivatives have been identified as efficient bifunctional organocatalysts for the direct Michael addition of cyclohexanone to a wide range of nitroalkenes. The desired Michael adducts were obtained in high chemical yields and excellent stereoselectivities (up to 99/1 dr and 95% ee). The Royal Society of Chemistry 2011.
